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Biocomposite Nanomaterials for Electrochemical Biosensors

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Handbook of Nanoelectrochemistry

Abstract

Biocomposite nanomaterials composed of biological receptors and various inorganic and organic components have recently attracted a great deal of interest due to their peculiar properties and use in electrochemical sensors and biosensors. Recognition systems based on biocomposite nanomaterials were developed as highly sensitive and selective elements for electrochemical biosensors technology. Since the development of the first marketed biosensor almost 25 years ago, the biosensor technology has benefited from the use of electrodes modified with nanostructured biomaterials that enhanced the selectivity and the sensitivity of the measurements. The use of electrochemical methods for in situ preparation and characterization of biocomposite nanomaterials resulted in the occurrence of unique electrocatalytic properties and enhanced analytical performances. In recent years, there has also been much progress in understanding the electrochemical behavior of biological elements, such as enzymes, antibodies, cells, tissues, peptides, and nucleic acids, immobilized within conducting polymer-based composite nanomaterials, as well as the synergy between their biocatalytic activity and affinity and the electrocatalytic activity of various inorganic/organic fillers towards the target analytes.

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Acknowledgments

S. L. greatly acknowledges the financial support by a grant of the Romanian National Authority for Scientific Research, CNCS–UEFISCDI, project number PN-II-ID-PCE-2011-3-0271.

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Authors and Affiliations

  1. Department of Analytical Chemistry and Environmental Engineering, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, Polizu Street 1-5, 011061, Bucharest, Romania

    Stelian Lupu

  2. Department of Organic Chemistry, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, Polizu Street 1-5, 011061, Bucharest, Romania

    Paul Cătălin Balaure

  3. Laboratory of Electrochemistry, Institute of Physical Chemistry “Ilie Murgulescu” of the Romanian Academy, Splaiul Independentei 202, 060021, Bucharest, Romania

    Cecilia Lete

  4. Department of Physical Chemistry, Faculty of Chemistry, University of Bucharest, Bld. Regina Elisabeta 4-12, 030018, Bucharest, Romania

    Constantin Mihailciuc

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  1. Stelian Lupu
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  2. Paul Cătălin Balaure
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  3. Cecilia Lete
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  4. Constantin Mihailciuc
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Correspondence to Stelian Lupu .

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Editors and Affiliations

  1. Materials Engineering, Tarbiat Modares University, Tehran, Iran

    Mahmood Aliofkhazraei

  2. Department of Surface Engineering, Central of Metallurgical Research and Development Institute, Cairo, Egypt

    Abdel Salam Hamdy Makhlouf

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Lupu, S., Balaure, P.C., Lete, C., Mihailciuc, C. (2015). Biocomposite Nanomaterials for Electrochemical Biosensors. In: Aliofkhazraei, M., Makhlouf, A. (eds) Handbook of Nanoelectrochemistry. Springer, Cham. https://doi.org/10.1007/978-3-319-15207-3_39-1

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  • DOI: https://doi.org/10.1007/978-3-319-15207-3_39-1

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  • Online ISBN: 978-3-319-15207-3

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