Abstract
Conyza canadensis (C. canadensis) ((L.) Cronquist) has been used as medicinal herb in many countries. The antifungal activity of C. canadensis which was extracted by different solvents including ethanol, ethyl acetate and n-hexane was examined by using agar well diffusion method and minimum inhibitory concentration method. Two fungal pathogens used to determine the bioactive activity of these extracts were Candida albicans (C. albicans) and Trichosporon insectorum (T. insectorum). Among these three extracts using different polarity solvents, the antifungal activity of C. canadensis extracted with ethyl acetate showed the highest antifungal activity against both tested fungal pathogens. Conversely, the extracts with ethanol and n-hexane didn’t show any activity towards the tested fungi in the agar well diffusion experiment. C. canadensis extracted with ethyl acetate showed its high effect against T. insectorum with 45.33 mm of inhibition zone, antifungal activity was lower to C. albicans which was about 25.33 mm of inhibition zone. Minimum inhibitory concentration (MIC) of ethanol, ethyl acetate and n-hexane extract against C. albicans were 250, 15, and 500 mg/ml, respectively. MIC values with extracts in ethanol and ethyl acetate solvents in case of T. insectorum were lower than which of C. albicans. The particular MIC values of extracts in ethanol, ethyl acetate and n-hexane against C. albicans were 63, 8 and 1000 mg/ml, respectively.
Access provided by Autonomous University of Puebla. Download to read the full chapter text
Chapter PDF
Similar content being viewed by others
Keywords
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this paper
Cite this paper
Phuong, N.B., Lien, N.T.T., Hoai, N.T.T. (2015). Antifungal Activity of Conyza canadensis ((L.) Cronquist) Collected in Northern Viet Nam. In: Toi, V., Lien Phuong, T. (eds) 5th International Conference on Biomedical Engineering in Vietnam. IFMBE Proceedings, vol 46. Springer, Cham. https://doi.org/10.1007/978-3-319-11776-8_88
Download citation
DOI: https://doi.org/10.1007/978-3-319-11776-8_88
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-11775-1
Online ISBN: 978-3-319-11776-8
eBook Packages: EngineeringEngineering (R0)