Abstract
In the late 1950s, transplant models were developed in dogs for all of the intra-abdominal organs (Fig. 1). The most fruitful of these efforts involved the liver (Table 1) (Starzl TE (1969a) In: Starzl TE (ed) Experience in hepatic transplantation. WB Saunders, Philadelphia). In addition to its direct clinical application, the research in liver transplantation yielded new information about the metabolic interrelations of the intra-abdominal viscera in disease and health; a more profound understanding of the mechanisms of organ alloengraftment; and the addition of new nontransplant procedures to the treatment armamentarium against gastrointestinal diseases.
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References
Ackerman JR, Snell ME (1968) Cadaveric renal transplantation. Br J Urol 40:515–521
Benichou J, Halgrimson CG, Weil R III et al (1977) Canine and human liver preservation for 6 to 18 hours by cold infusion. Transplantation 24:407–411
Billingham R, Brent L (1956) Quantitative studies on transplantation immunity. IV. Induction of tolerance in newborn mice and studies on the phenomenon of runt disease. Philos Trans R Soc Lond 242:439–477
Billingham RE, Krohn PL, Medawar PB (1951) Effect of cortisone on survival of skin homografts in rabbits. Br Med J 1:1157–1163
Bismuth H, Houssin D (1984) Reduced-size orthotopic liver graft in hepatic transplantation in children. Surgery 95:367–370
Bollman JL (1961) The animal with an Eck fistula. Physiol Rev 41:607–621
Brettschneider L, Daloze PM, Huguet C et al (1968a) The use of combined preservation techniques for extended storage of orthotopic liver homografts. Surg Gynecol Obstet 126:263–274
Brettschneider L, Tong JL, Boose DS et al (1968b) Specific bacteriologic problems after orthotopic liver transplantation in dogs and pigs. Arch Surg 97:313–322
Broelsch CE, Neuhaus P, Burdelski M et al (1984) Orthotope transplantation von Lebesegmenten bei mit Gallengall8llatresien. (Orthotopic transplantation of hepatic segments in infants with biliary atresia). In: Kolsowski L (ed) Chirurgisches Forum 1984, F Experim U Klimische Forschung Hrsga. Springer, Berlin, pp 105–109
Broelsch CE, Emond J, Whitington PF et al (1990) Application of reduced-size liver transplants as split grafts, auxiliary orthotopic grafts, and living related segmental transplants. Ann Surg 212:368–375
Busuttil RW, DeCarlis LG, Mihaylov PV, Gridelli B, Fassati LR, Starzl TE (2012) The first report of orthotopic liver transplantation in the western world. Am J Transplant 12:1385–1387
Calne RY (1960) The rejection of renal homografts: inhibition in dogs by 6-mercaptopurine. Lancet 1:417–418
Calne RY, Murray JE (1961) Inhibition of the rejection of renal homografts in dogs by Burroughs Wellcome 57-322. Surg Forum 12:118–120
Calne RY, Williams R (1968) Liver transplantation in man. I. Observations on technique and organization in five cases. Br Med J 4:535–550
Calne RY, Sells RA, Pena J et al (1969) Induction of immunological tolerance by porcine liver allografts. Nature 223:472–474
Calne RY, Rolles K, White DJG et al (1979) Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers. Lancet 2:1033–1036
Carrel A (1902) La technique operatoire des anastomoses vasculaires et la transplantation des visceres. Lyon MEO 98:859–864
Child CG, Barr D, Holswade GR, Harrison CS (1953) Liver regeneration following portacaval transposition in dogs. Ann Surg 138:600–608
Craddock GN, Nordgren SR, Reznick RD et al (1983) Small bowel transplantation in the dog using cyclosporine. Transplantation 35:284–288
Cutropia F, Coratolo F, Spinerta A et al (1972) Experimental orthotopic liver transplantation. Rev Esp Enferm Apar Dig 38:553–570
DeJode LR, Howard JM (1962) Studies in pancreaticoduodenal homotransplantation. Surg Gynecol Obstet 114:553–558
Deltz E, Ulrich K, Scbach T et al (1986) Graft-versus-host reaction in small bowel transplantation and possibilities for its circumvention. Am J Surg 151:379–386
Deltz E, Schroeder P, Gundlach M et al (1990) Successful clinical small-bowel transplantation. Transplant Proc 22:2501
Demirleau, Noureddine, Vignes et al (1964) Tentative d’homograffe hepatique (Attempted hepatic homograft). Mem Acad Chir (Paris) 90:177–179
Dempster WJ, Lennox B, Boag JW (1950) Prolongation of survival of skin homotransplants in the rabbit by irradiation of the host. Br J Exp Pathol 131:670–679
Denmark SW, Shaw BW, Starzl TE, Griffith BP (1983) Veno-venous bypass without systemic anticoagulation in canine and human liver transplantation. Surg Forum 34:380–382
Diliz-Perez HS, McClure J et al (1984) Successful small bowel allotransplantations in dogs with cyclosporine and prednisone. Transplantation 37:126–129
Fisher B, Russ C, Updegratf H, Fisher ER (1954) Effect of increased hepatic blood flow upon liver regeneration. Arch Surg 69:263–272
Francavilla A, Starzl TE, Porter K et al (1991) Screening for candidate hepatic growth factors by selective portal infusion after canine Eck fistula. Hepatology 14:665–670
Francavilla A, Hagiya M, Porter KA et al (1994a) Augmenter of liver regeneration (ALR): its place in the universe of hepatic growth factors. Hepatology 20:747–757
Francavilla A, Zeng Q, Polimeno L, Carr BI, Sun D, Van Thiel DH, Starzl TE (1994b) Small-for-size liver transplanted into larger recipient: a model of hepatic regeneration. Hepatology 19:210–216
Franksson C (1984) Survival of homo grafts of skin in rats depleted of lymphocytes by chronic drainage from the thoracic duct. Lancet 1:1331–1332
Gandhi CR, Chaillet JR, Nalesnik M et al (2015) Liver-specific deletion of augmenter of liver regeneration induces accelerated steatohepatitis in mice. Gastroenterology 148:379–391
Giorda R Haigya M, Seki T et al (1996) Analysis of the structure and expression of ALR gene. Molecular Med 2:97–108
Goodrich EO Jr, Welch HF, Nelson JA et al (1956) Homotransplantation of the canine liver. Surgery 39:244–251
Goodwin WE, Martin DC (1963) Transplantation of the kidney. Urol Surv 13:229–248
Goulet O, Revillon Y, Brousse N et al (1992) Successful small bowel transplantation in an infant. Transplantation 53:940–943
Grant O, Duff J, Zhong R et al (1988) Successful intestinal transplantation in pigs treated with cyclosporine. Transplantation 45:279–284
Grant D, Wall W, Mimeault R et al (1990) Successful small bowel/liver transplantation. Lancet 335:181–184
Griffith BP, Shaw BW, Hardesty RL et al (1985) Venovenous bypass without systemic anticoagulation for transplantation of the human liver. Surg Gynecol Obstet 160:270–272
Groth CG (1972) Landmarks in clinical renal transplantation. Surg Gynecol Obstet 134:323–328
Groth CG, Porter KA, Otte JB et al (1968) Studies of blood flow and ultrastructural changes in rejecting and non-rejecting canine orthotopic liver homografts. Surgery 63:31–38
Hagiya M, Francavilla A, Polimeno L et al (1994) Cloning and sequence analysis of the rat augmenter of liver regeneration ALR) gene: Expression of biology active recombinant ALR and demonstration of tissue distribution. Proc Natl Acad Sci 91:8142–8146
Hamburger J, Vaysse J, Crosnier J et al (1962) Renal homotransplantation in man after radiation of the recipient. Am J Med 32:854–871
Houssay BA (1929) Technique de la greffe pancreaticoduodenal au coo. C R Soc Biol 100:138–140
Hume DM, Magee JH, Kauffman HM et al (1963) Renal transplantation in man in modified recipients. Ann Surg 158:608–644
Idezuki Y, Feemster JA, Dietzman RH, Lillehei RE (1968) Experimental pancreaticoduodenal preservation and transplantation. Surg Gynecol Obstet 126:1002–1014
Jamieson NY, Sundberg R, Lindell S et al (1988) Successful 24- to 30-hour preservation of the canine liver: a preliminary report. Transplant Proc 20(Suppl 1):945–947
Kalayoglu M, Sollinger WH, Stratta RL et al (1988) Extended preservation of the liver for clinical transplantation. Lancet 1:617–619
Kam I, Lynch S, Savanas G et al (1987) Evidence that host size determines liver size: studies in dogs receiving orthotopic liver transplants. Hepatology 7:362 366
Kamada N (1985) The immunology of experimental liver transplantation in the rat. Immunology 55:369–389
Kang YO, Martin DJ, Marquez J et al (1985) Intraoperative changes in blood coagulation and thrombelastographic monitoring in liver transplantation. Anesth Analg 64:888–896
Kelly WD, Lillehei RC, Merkel FK et al (1967) Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy. Surgery 61:827–837
Kuss R, Legrain M, Mathe G et al (1962) Homologous human kidney transplantation. Experience with six patients. Postgrad Med J 38:528–531
Lillehei RC, Goon B, Miller FA (1959) The physiologic response of the small bowel of the dog to ischemia, including prolonged in vitro preservation of the bowel with successful replacement and survival. Ann Surg 150:543–560
Mann FC (1944) The William Henry Welch Lectures: II. Restoration and pathologic reactions of the liver. Mt Sinai Hosp II, pp 65–74
Marchioro TL, Huntley RT, Waddell WR, Starzl TE (1963) Extracorporeal perfusion for obtaining postmortem homografts. Surgery 54:900–911
Marchioro TL, Axtell HK, LaVia MF et al (1964) The role of adrenocortical steroids in reversing established homograft rejection. Surgery 55:412–417
Marchioro TL, Porter KA, Dickinson TC et al (1965) Physiologic requirements for auxiliary liver homotransplantation. Surg Gynecol Obstet 121:17–31
Marchioro TL, Porter KA, Brown BI et al (1967) The effect of partial portacaval transposition on the canine liver. Surgery 61:723–732
Mazzaferro V, Porter KA, Scotti-Foglieni CL et al (1990) The hepatotrophic influence of cyclosporine. Surgery 107:533–539
McBride RA, Wheeler HB, Smith LL et al (1962) Homotransplantation of the canine liver as an orthotopic vascularized graft. Histologic and functional correlations during residence in the new host. Am J Pathol 41(50):1–520
Medawar PB (1944) The behavior and fate of skin autografts and skin homografts in rabbits. J Anat 78:176–199
Medawar PB (1945) Second study of behavior and fate of skin homografis in rabbits. J Anat 79:157
Meeker WR, Condie R, Weiner D et al (1959) Prolongation of skin homograft survival in rabbits by 6-mercaptopurine. Proc Soc Exp BioI Med 102:459–461
Merkel FK, Jonasson O, Bergan JJ (1972) Procurement of cadaver donor organs. Evisceration technique. Transplant Proc 4:585–589
Meyer WH Jr, Starzl TE (1959a) The reverse portacaval shunt. Surgery 45:531–534
Meyer WH Jr, Starzl TE (1959b) The effect of Eck and reverse Eck fistula in dogs with experimental diabetes mellitus. Surgery 45:760–764
Monchik GJ, Russell PS (1971) Transplantation of the small bowel in the rat: technical and immunologic considerations. Surgery 70:693–702
Moore FD (1964) Give and take: the development of tissue transplantation. WB Saunders, Philadelphia
Moore FD, Smith LL, Burnap TK et al (1959) One-stage homotransplantation of the liver following total hepatectomy in dogs. Transplant Bull 6:103–110
Moore FD, Wheeler HB, Demissianos HV et al (1960) Experimental whole organ transplantation of the liver and of the spleen. Ann Surg 152:374–387
Moore FD, Birtch AG, Dagher F et al (1964) Immunosuppression and vascular insufficiency in liver transplantation. Ann N Y Acad Sci 102:729–738
Morgan JA (1951) The influence of cortisone on the survival of homografts of skin in the rabbit. Surgery 30:506–515
Murray JE, Merrill JP, Dammin GJ et al (1960) Study of transplantation immunity after total body irradiation: clinical and experimental investigation. Surgery 48:272–284
Murray JE, Merrill JP, Dammin GJ et al (1962) Kidney transplantation in modified recipients. Ann Surg 156:337–355
Murray JE, Merrill JP, Harrison JH et al (1963) Prolonged survival of human-kidney homografts by immunosuppressive drug therapy. N Engl J Med 268:1315–1323
Najarian JS, Ferguson RM, Sutherland DE et al (1982) Fractionated total lymphoid irradiation as preparative immunosuppression in high risk renal transplantation. Ann Surg 196:442–452
Picache RS, Kapur BML, Starzl TE (1970) The effect of liver disease on the need for venous decompression during the anhepatic phase of canine orthotopic liver transplantation. Surgery 67:319–321
Putnam CW, Porter KA, Starzl TE (1976) Hepatic encephalopathy and light and electron micrographic changes of the baboon liver after portal diversion. Ann Surg 184:155–161
Ramsey G, Nusbacher J, Starzl TE, Lindsay GD (1984) Isohemagglutinins of graft origin after ABO-unmatched liver transplantation. N Engl J Med 311:1167–1170
Ricour C, Revillon Y, Arnaud-Battandier F et al (1983) Successful small bowel allografts in piglets using cyclosporine. Transplant Proc 15:3019–3026
Schwartz R, Dameshek W (1960) The effects of 6-mercaptopurine on homograft reactions. J Clin Invest 39:952–958
Shaw BW, Martin DJ, Marquez JM et al (1984) Venous bypass in clinical liver transplantation. Ann Surg 200:524–534
Shaw BW Jr, Iwatsuki S, Bron K, Starzl TE (1985) Portal vein grafts in hepatic transplantation. Surg Gynecol Obstet 161:66–68
Sheil AGR, Thompson JF, Stevens MS et al (1987) Mesoportal graft for thrombosed portal vein in liver transplantation. Clin Transpl 1:18–21
Starzl TE (1960) In Moore et al (1960) Discussion Ann Surg 152:386–387
Starzl TE (1964) Experience in renal transplantation. WB Saunders, Philadelphia, pp 68–71
Starzl TE (1969a) In: Starzl TE (ed) Experience in hepatic transplantation. WB Saunders, Philadelphia, pp 1–554
Starzl TE (1969b) Infectious complications, excluding partial hepatic gangrene. In: Starzl TE (ed) Experience in hepatic transplantation. WB Saunders, Philadelphia, pp 329–347
Starzl TE (1969c) Early liver rejection in patients without hepatic gangrene. In: Starzl TE (ed) Experience in hepatic transplantation. WB Saunders, Philadelphia, pp 277–307
Starzl TE (1969d) Immunosuppression in man. In: Starzl TE (ed) Experience in hepatic transplantation. WB Saunders, Philadelphia, pp 242–276
Starzl TE (1969e) Experience in hepatic transplantation. WB Saunders, Philadelphia, pp 45–48
Starzl TE (1992a) A trip south. In: Starzl TE (ed) Puzzle people: memoirs of a transplant surgeon. University of Pittsburgh Press, Pittsburgh, pp 47–58
Starzl TE (1992b) The failed liver transplantation trials. In: Starzl TE (ed) The puzzle people: memoirs of a transplant surgeon. University of Pittsburgh Press, Pittsburgh, pp 96–105
Starzl TE (1992c) The donors and the organs. In: Starzl TE (ed) The puzzle people: memoirs of a transplant surgeon. University of Pittsburgh Press, Pittsburgh, pp 145–154
Starzl TE (1992d) A Pyrrhic victory. In: Starzl TE (ed) The puzzle people: memoirs of a transplant surgeon. University of Pittsburgh Press, Pittsburgh, pp 162–172
Starzl TE (1992e) Icebergs and hammer blows. In: Starzl TE (ed) The puzzle people: memoirs of a transplant surgeon. University of Pittsburgh Press, Pittsburgh, pp 173–196
Starzl TE (1992f) The little drummer girls. In: Starzl TE (ed) The puzzle people: memoirs of a transplant surgeon. University of Pittsburgh Press, Pittsburgh, pp 318–333
Starzl TE (2015a) The birth of organ transplantation: with particular reference to alloengraftment mechanisms. Molecular Medicine 21
Starzl TE, Demetris AJ (1990) Liver transplantation: a 31-year perspective. Year Book, Chicago, pp 38–41
Starzl TE, Fung JJ (2010) Themes of liver transplantation. Hepatology 51:1869–1884
Starzl TE, Kaupp HA Jr (1960) Mass homotransplantation of abdominal organs in dogs. Surg Forum 11:28–30
Starzl TE, Terblanche J (1979) Hepatotrophic substances. In: Popper H, Schaffner F (eds) Progress in liver diseases, vol 6. Grone & Stratton, New York, pp 135–152
Starzl TE, Bernhard VM, Benvenuto R, Cortes N (1959) A new method for one stage hepatectomy in dogs. Surgery 46:880–886
Starzl TE, Kaupp HA Jr, Brock DR et al (1960) Reconstructive problems in canine liver homotransplantation with special reference to the postoperative role of hepatic venous flow. Surg Gynecol Obstet 111:733–743
Starzl TE, Kaupp HA Jr, Brock DR, Linman JW (1961) Studies on the rejection of the transplanted homologous dog liver. Surg Gynecol Obstet 112:135–144
Starzl TE, Kaupp HA Jr, Brock DR et al (1962) Homotransplantation of multiple visceral organs. Am J Surg 103:219–229
Starzl TE, Marchioro TL, Waddell WR (1963a) The reversal of rejection in human renal homografts with subsequent development of homograft tolerance. Surg Gynecol Obstet 117:385–395
Starzl TE, Marchioro TL, Talmage DW, Waddel WR (1963b) Splenectomy and thymectomy in human renal transplantation. Proc Soc Exp Biol Med 113:929–932
Starzl TE, Marchioro TL, Von Kaulla KN et al (1963c) Homotransplantation of the liver in humans. Surg Gynecol Obstet 117:659–676
Starzl TE, Marchioro TL, Rowlands DT Jr et al (1964) Immunosuppression after experimental and clinical homotransplantation of the liver. Ann Surg J 60:411–439
Starzl TE, Marchioro TL, Porter KA et al (1965) Factors determining short- and long-term survival after orthotopic liver homotransplantation in the dog. Surgery 58:131–155
Starzl TE, Marchioro TL, Porter KA et al (1967) The use of heterologous antilymphoid agents in canine renal and liver homotransplantation and in human renal homotransplantation. Surg Gynecol Obstet 124:301–318
Starzl TE, Groth CG, Brettschneider L et al (1968) Orthotopic homotransplantations of the human liver. Ann Surg 168:392–415
Starzl TE, Putnam CW, Halgrimson CG et al (1971) Cyclophosphamide and whole organ transplantation in humans. Surg Gynecol Obstet 133:981–991
Starzl TE, Francavilla A, Halgrimson CG et al (1973) The origin, hormonal nature, and action of hepatotrophic substances in portal venous blood. Surg Gynecol Obstet 137:179–199
Starzl TE, Poner KA, Kashiwagi N et al (1975a) The effect of diabetes mellitus on portal blood hepatotrophic factors in dogs. Surg Gynecol Obstet 140:549–562
Starzl TE, Porter KA, Kashiwagi N, Putnam CW (1975b) Portal hepatotrophic factors, diabetes mellitus and acute live, atrophy, hypertrophy and regeneration. Surg Gynecol Obstet 141:843–858
Starzl TE, Lee IY, Porter KA, Putnam CW (1975c) The influence of portal blood upon lipid metabolism in normal and diabetic dogs and baboons. Surg Gynecol Obstet 140:381–396
Starzl TE, Watanabe K, Porter KA, Putnam CW (1976) Effects of insulin, glucagon, and insulin/glucagon infusions on liver morphology and cell division after complete portacaval shunt in dogs. Lancet 1:821–825
Starzl TE, Putnam CW, Hansbrough JF et al (1977) Biliary complications after liver transplantation: with special reference to the biliary cast syndrome and techniques of secondary duct repair. Surgery 81:212–221
Starzl TE, Francavilla A, Porter KA, Benichou J (1978a) The effect upon the liver of evisceration with or without hormone replacement. Surg Gynecol Obstet 146:524–531
Starzl TE, Francavilla A, Porter KA et al (1978b) The effect of splanchnic viscera removal upon canine liver regeneration. Surg Gynecol Obstet 147:193–207
Starzl TE, Joncs AF, Terblanche J et al (1979a) Growth-stimulating factor in regenerating canine liver. Lancet 1:127–130
Starzl TE, Weil R, Koep LJ et al (1979b) Thoracic duct drainage before and after cadaveric kidney transplantation. Surg Gynecol Obstet 149:815–821
Starzl TE, Halgrimson CG, Koep LJ et al (1979c) Vascular homografts from cadaveric organ donors. Surg Gynecol Obstet 149:737
Starzl TE, Weil R, Iwatsuki S et al (1980) The use of cyclosporin A and prednisone in cadaver kidney transplantation. Surg Gynecol Obstet 151:17–26
Starzl TE, Klintmalm GBO, Porter KA et al (1981) Liver transplantation with the use of cyclosporin A and prednisone. N Engl J Med 305:266–269
Starzl TE, Iwatsuki S, van Thiel DH et al (1982) Evolution of liver transplantation. Hepatology 2:614–636
Starzl TE, Porter KA, Francavilla A (1983) The Eck fistula in animals and humans. Curr Probl Surg 20:687–752
Starzl TE, Hakala TR, Shaw BW Jr et al (1984) A flexible procedure for multiple cadaveric organ procurement. Surg Gynecol Obstet 158:223–230
Starzl TE, Miller C, Broznick B, Malcowka L (1987) An improved technique for multiple organ harvesting. Surg Gynecol Obstet 165:343–348
Starzl TE, Rowe M, Todo S et al (1989a) Transplantation of multiple abdominal viscera. JAMA 26:1449–1457
Starzl TE, Todo S, Fung J et al (1989b) FK506 for human liver, kidney, and pancreas transplantation. Lancet 2:1000–1004
Starzl TE, Todo S, Tzakis A (1989c) Abdominal organ cluster transplantation for the treatment of upper abdominal malignancies. Ann Surg 210:374–386
Starzl TE, Demetris AJ, Van Thiel DH (1989d) Medical progress: liver transplantation, part I. N Engl J Med 321:1014–1022
Starzl TE, Demetris AJ, Van Thiel DH (1989e) Medical progress: liver transplantation, part II. N Engl J Med 321:1092–1099
Starzl TE, Schroter GPJ, Hartmann NJ et al (1990) Long term (25 year) survival after renal homotransplantation-the world experience. Transplant Proc 22:2361–2365
Starzl TE, Todo S, Tzakis A et al (1991a) The many faces of multivisceral transplantation. Surg Gynecol Obstet 172:335–344
Starzl TE, Porter KA, Mazzaferro V et al (1991b) Hepatotrophic effects of FK 506 in dogs. Transplantation 51:67–70
Starzl TE, Demetris AJ, Murase N et al (1992) Cell migration, chimerism, and graft acceptance. Lancet 339:1579–1582
Starzl TE, Todo S, Tzakis A, Fung J (1993a) The transplantation of gastrointestinal organs. Gastroenterology 104:673–679
Starzl TE, Demetris AJ, Trucco M et al (1993b) Cell migration and chimerism after whole organ transplantation: the basis of graft acceptance. Hepatology 17:1127–1152
Starzl TE, Demetris AJ, Trucco M et al (1993c) Chimerism and donor-specific nonreactivity 27 to 29 years after kidney allotransplantation. Transplantation 55:1272–1277
Starzl TE, Demetris AJ, Trucco M et al (1993d) Chimerism after liver transplantation for type IV glycogen storage disease and type I Gaucher’s disease. N Engl J Med 328:745–749
Starzl TE, Demetris AJ, Murase N et al (1996) The lost chord: microchimerism. Immunol Today 17:577–584
Starzl TE, Murase N, Eghtesad B et al (2015b) Leukocyte chimerism -Meaning and consequences. In: Busuttil RW, Klintmalm GB (eds) The transplantation of the liver, 3rd edn. W.B. Saunders, Philadelphia, pp 1227–1244
Stieber AC, Zetti G, Todo S et al (1991) The spectrum of portal vein thrombosis. Ann Surg 213:199–206
Strober S, Slavin S, Fuks Z et al (1979) Transplantation tolerance after total lymphoid irradiation. Transplant Proc 11:1032–1038
Strong RW, Lynch SV, Ong TH et al (1990) Successful liver transplantation from a living donor to her son. N Engl J Med 322:1505–1507
Todo S, Nery J, Yanaga K et al (1989) Extended preservation of human liver grafts with UW solution. JAMA 261:711–714
Todo S, Fung JJ, Starzl TE et al (1990) Liver, kidney, and thoracic organ transplantation under FK506. Ann Surg 212:295–305
Todo S, Tzakis AG, Abu-Elmagd K et al (1992) Intestinal transplantation in composite visceral grafts or alone. Ann Surg 216:223–234
Todo S, Tzakis A, Reyes J et al (1993) Intestinal transplantation in humans under FK 506. Transplant Proc 25:1198–1199
Trentin JJ (1956) Mortality and skin transplantability in X-irradiated mice receiving isologous or heterologous bone marrow. Proc Soc Exp Biol Med 92:688–693
Tzakis A, Todo S, Starzl TE (1989a) Orthotopic liver transplantation with preservation of the inferior vena cava. Ann Surg 210:649–652
Tzakis A, Todo S, Stieber A, Starzl TE (1989b) Venous jump grafts for liver transplantation in patients with portal vein thrombosis. Transplantation 48:530–531
Valdivia LA, Demetria AJ, Fung JJ et al (1993) Successful hamster to rat liver xenotransplantation under FK506 immunosuppression induces unresponsiveness to hamster heart and skin. Transplantation 55:659–661
Wall WJ, CaIne RY, Berbertson BM et al (1977) Simple hypothermic preservation for transporting human livers long distance for transplantation. Transplantation 23:210–216
Welch CS (1955) A note on transplantation of the whole liver in dogs. Transplant Bull 2:54–55
Woodruff WMA (1960) The transplantation of tissues and organs. Charles C Thomas, Springfield
Woodruff MFA, Robson JS, Nolan B et al (1963) Homotransplantation of kidney in patients treated with preoperative administration of antimetabolite (lmuran). Lancet 2:675–682
Zukoski CF, Lee HM, Hume DM (1960) The prolongation of functional survival of canine renal homografts by 6-mercaptopurine. Surg Forum 11:470–472
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Starzl, T.E. (2016). History of Liver and Other Splanchnic Organ Transplantation. In: Doria, C. (eds) Contemporary Liver Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-05543-5_1-2
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History of Liver and Other Splanchnic Organ Transplantation- Published:
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DOI: https://doi.org/10.1007/978-3-319-05543-5_1-2
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History of Liver and Other Splanchnic Organ Transplantation- Published:
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DOI: https://doi.org/10.1007/978-3-319-05543-5_1-1