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Biodegradable Inorganic Nanocomposites

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Handbook of Biodegradable Materials

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Abstract

Plant-sourced materials (starch, cellulose, and other polysaccharides), animal products (proteins), and polymers produced chemically from naturally generated monomers (polylactic acid or PLA) are becoming less attractive. Accordingly, the development of nanocomposites by combinations of polymers and inorganic compounds from entirely or partially renewable resources allow exceptional attributes and attracted attention in areas ranging from materials science to biology or medicine. It was shown that nanoscale reinforcements in inorganic composite materials delivered the characteristics enhancement such as decreased hydrophilicity, increased mechanical qualities substantially, and enhanced bioactivity compared to synthetic and natural polymers, which did not display these properties on their own. Indeed, the development of novel biodegradable inorganic nanocomposites has reduced the possible human health risks associated with the pharmaceutical and pesticide sectors through nano-based agricultural commodities and the discovery of enhanced eco-friendly bioactive compounds. The chapter aims to provide details of nanocomposites based on biodegradable polymers and inorganic nanocomposites, preparation methods from wet to dry approaches, and recent applications, especially in the biomedical and healthcare sectors. This emerging idea will enhance the scope of bionanocomposites materials for sustainable products development with improved properties than commercially existing synthetic or natural polymer-based biodegradable materials.

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Abbreviations

0D:

Zero-dimensional

1D:

One-dimensional

2D:

Two-dimensional

3D:

Three-dimensional

AgNPs:

Silver Nanoparticles

BPA:

Bisphenol A

CNC:

Cellulose Nanocrystals

CNTs:

Carbon Nanotubes

CVD:

Chemical Vapor Deposition

DMA:

Dynamic mechanical analysis

DSC:

Differential scanning calorimetry

FESEM:

Field Emission Scanning Electron Microscope

GO:

Graphene Oxide

hMSC:

Human Mesenchymal Stem Cells

HPLC:

High-Performance Liquid Chromatography

hUCMSCs:

Human Umbilical Cord Matrix Stem Cells

KCl-HCl:

potassium chloride-hydrochloric acid

MFC:

Micro Fibrillated Cellulose

Mg-Zn:

Magnesium-zinc

MMT:

Montmorillonite

MWCNTs:

Multi-Walled Carbon Nanotubes

PANI:

Polyaniline

PBS:

Phosphate buffer solution

PEO:

Poly(ethylene oxide)

PLA:

Polylactic Acid

PMMA:

Poly(methyl methacrylate)

SBF:

Simulated Body Fluids

SNC:

Starch nanocrystals

SNP:

Starch nanoparticles

SPR:

Surface Plasmon Resonances

TEM:

Transmission Electron Microscope

Tg:

Glass transition temperature

Tm:

Melting point

References

  1. Mohanty AK, Misra M, and Hinrichsen G (2000) Biofibres, biodegradable polymers and biocomposites: An overview. Macromolecular Materials and Engineering 276(1):1–24

    Google Scholar 

  2. Okunola A A, Kehinde I O, Oluwaseun A, and Olufiropo E A (2019) Public and Environmental Health Effects of Plastic Wastes Disposal: A Review. Journal of Toxicology and Risk Assessment 5(2)

    Google Scholar 

  3. Omerovic N, Djisalov M, Zivojevic K, Mladenovic M, Vunduk J, Milenkovic I, Knezevic NZ, Gadjanski I, and Vidic J (2021) Antimicrobial nanoparticles and biodegradable polymer composites for active food packaging applications. Compr Rev Food Sci Food Saf 20(3):2428–2454

    Google Scholar 

  4. Santhosh R, Nath D, and Sarkar P (2021) Novel food packaging materials including plant-based byproducts: A review. Trends in Food Science & Technology 118:471–489

    Google Scholar 

  5. Joseph B, Krishnan S, Sagarika VK, Tharayil A, Kalarikkal N, and Thomas S (2020) Bionanocomposites as industrial materials, current and future perspectives: A review. Emergent Materials 3:711–725

    Google Scholar 

  6. Alshehrei F (2017) Biodegradation of synthetic and natural plastic by microorganisms. Journal of Applied & Environmental Microbiology 5(1):8–19

    Google Scholar 

  7. Arora B, Bhatia R, and Attri P, Bionanocomposites: Green materials for a sustainable future, in New polymer nanocomposites for environmental remediation. 2018, Elsevier. p. 699–712.

    Google Scholar 

  8. Karthika M, Shaji N, Johnson A, Neelakandan MS, Gopakumar D, and Thomas S (2019) Biodegradation of green polymeric composites materials. Bio Monomers for Green Polymeric Composite Materials:141–159

    Google Scholar 

  9. Kausar A, Conducting Polymer-Based Nanocomposites: Fundamentals and Applications. 2021: Elsevier.

    Google Scholar 

  10. Tang X, Kumar P, Alavi S, and Sandeep K (2012) Recent advances in biopolymers and biopolymer-based nanocomposites for food packaging materials. Critical reviews in food science and nutrition 52(5):426–442

    Google Scholar 

  11. Zaghloul MYM, Zaghloul MMY, and Zaghloul MMY (2021) Developments in polyester composite materials–An in-depth review on natural fibres and nano fillers. Composite Structures:114698

    Google Scholar 

  12. Mariano M, El Kissi N, and Dufresne A (2014) Cellulose nanocrystals and related nanocomposites: review of some properties and challenges. Journal of Polymer Science Part B: Polymer Physics 52(12):791–806

    Google Scholar 

  13. Du H, Liu W, Zhang M, Si C, Zhang X, and Li B (2019) Cellulose nanocrystals and cellulose nanofibrils based hydrogels for biomedical applications. Carbohydrate polymers 209:130–144

    Google Scholar 

  14. Watkins D, Nuruddin M, Hosur M, Tcherbi-Narteh A, and Jeelani S (2015) Extraction and characterization of lignin from different biomass resources. Journal of Materials Research and Technology 4(1):26–32

    Google Scholar 

  15. Samaddar P, Kumar S, and Kim K-H (2019) Polymer hydrogels and their applications toward sorptive removal of potential aqueous pollutants. Polymer Reviews 59(3):418–464

    Google Scholar 

  16. Pérez S and Bertoft E (2010) The molecular structures of starch components and their contribution to the architecture of starch granules: A comprehensive review. Starch-Stärke 62(8):389–420

    Google Scholar 

  17. Ojijo V and Ray SS (2013) Processing strategies in bionanocomposites. Progress in Polymer Science 38(10–11):1543–1589

    Google Scholar 

  18. Singh KR, Nayak V, and Singh RP (2021) Introduction to bionanomaterials: an overview. This content has been downloaded from IOPscience. Please scroll down to see the full text.

    Google Scholar 

  19. Mohanty F and Swain S, Bionanocomposites for food packaging applications, in Nanotechnology Applications in Food. 2017, Elsevier. p. 363–379.

    Google Scholar 

  20. Müller K, Bugnicourt E, Latorre M, Jorda M, Echegoyen Sanz Y, Lagaron JM, Miesbauer O, Bianchin A, Hankin S, and Bölz U (2017) Review on the processing and properties of polymer nanocomposites and nanocoatings and their applications in the packaging, automotive and solar energy fields. Nanomaterials 7(4):74

    Google Scholar 

  21. Vasile C (2018) Polymeric nanocomposites and nanocoatings for food packaging: A review. Materials 11(10):1834

    Google Scholar 

  22. Adrah K, Ananey-Obiri D, and Tahergorabi R, Development of Bio-Based and Biodegradable Plastics, in Handbook of Nanomaterials and Nanocomposites for Energy and Environmental Applications, OV Kharissova, LMT Martínez, BI Kharisov, Editors. 2020, Springer International Publishing: Cham. p. 1-25.

    Google Scholar 

  23. Armentano I, Puglia D, Luzi F, Arciola CR, Morena F, Martino S, and Torre L (2018) Nanocomposites based on biodegradable polymers. Materials 11(5):795

    Google Scholar 

  24. Hegde G, Abdul Manaf SA, Kumar A, Ali GAM, Chong KF, Ngaini Z, and Sharma KV (2015) Biowaste sago bark based catalyst free carbon nanospheres: waste to wealth approach. ACS Sustainable Chemistry & Engineering 5(9):2247–2253

    Google Scholar 

  25. Habeeb OA, Ramesh K, Ali GAM, and Yunus RM (2017) Low-cost and eco-friendly activated carbon from modified palm kernel shell for hydrogen sulfide removal from wastewater: adsorption and kinetic studies. Desalination and Water Treatment 84:205–214

    Google Scholar 

  26. Ali GAM, Manaf SAA, A D, Chong KF, and Hegde G (2016) Superior supercapacitive performance in porous nanocarbons. Journal of Energy Chemistry 25(4):734–739

    Google Scholar 

  27. Habeeb OA, Ramesh K, Ali GAM, and Yunus RM (2017) Experimental design technique on removal of hydrogen sulfide using CaO-eggshells dispersed onto palm kernel shell activated carbon: Experiment, optimization, equilibrium and kinetic studies. Journal of Wuhan University of Technology-Mater. Sci. Ed. 32(2):305–320

    Google Scholar 

  28. Sadegh H, Ali GAM, Abbasi Z, and Nadagoud MN (2017) Adsorption of Ammonium Ions onto Multi-Walled Carbon Nanotubes. Studia Universitatis Babes-Bolyai Chemia 62(2):233–245

    Google Scholar 

  29. Alhanish A and Ali GAM, Recycling the Plastic Wastes to Carbon Nanotubes, in Waste Recycling Technologies for Nanomaterials Manufacturing, ASH Makhlouf, GAM Ali, Editors. 2021, Springer International Publishing: Cham. p. 701–727.

    Google Scholar 

  30. Georgakilas V, Perman JA, Tucek J, and Zboril R (2015) Broad family of carbon nanoallotropes: classification, chemistry, and applications of fullerenes, carbon dots, nanotubes, graphene, nanodiamonds, and combined superstructures. Chemical reviews 115(11):4744–4822

    Google Scholar 

  31. Ali GAM, Yusoff MM, and Chong KF (2016) Graphene Electrochemical production and its energy storage properties. ARPN Journal of Engineering and Applied Sciences 11(16):9712–9717

    Google Scholar 

  32. Thalji MR, Ali GAM, Poh S, and Feng K (2019) Solvothermal Synthesis of Reduced Graphene Oxide as Electrode Material for Supercapacitor Application. Chemistry of Advanced Materials 4(3):17–26

    Google Scholar 

  33. Ali GAM (2020) Recycled MnO2 Nanoflowers and Graphene Nanosheets for Low-Cost and High Performance Asymmetric Supercapacitor. Journal of Electronic Materials 49:5411–5421

    Google Scholar 

  34. Lee SP, Ali GAM, Algarni H, and Chong KF (2019) Flake size-dependent adsorption of graphene oxide aerogel. Journal of Molecular Liquids 277:175–180

    Google Scholar 

  35. Rajula MPB, Narayanan V, Venkatasubbu GD, Mani RC, and Sujana A (2021) Nano-hydroxyapatite: A driving force for bone tissue engineering. Journal of Pharmacy And Bioallied Sciences 13(5):11

    Google Scholar 

  36. Sopyan I, Mel M, Ramesh S, and Khalid K (2007) Porous hydroxyapatite for artificial bone applications. Science and Technology of Advanced Materials 8(1–2):116

    Google Scholar 

  37. van Hoof M, Wigren S, Duimel H, Savelkoul PH, Flynn M, and Stokroos RJ (2015) Can the hydroxyapatite-coated skin-penetrating abutment for bone conduction hearing implants integrate with the surrounding skin? Frontiers in surgery 2:45

    Google Scholar 

  38. Goto T, Kojima T, Iijima T, Yokokura S, Kawano H, Yamamoto A, and Matsuda K (2001) Resorption of synthetic porous hydroxyapatite and replacement by newly formed bone. Journal of orthopaedic science 6(5):444–447

    Google Scholar 

  39. Rumpel E, Wolf E, Kauschke E, Bienengräber V, Bayerlein T, Gedrange T, and Proff P (2006) The biodegradation of hydroxyapatite bone graft substitutes in vivo. Folia morphologica 65(1):43–48

    Google Scholar 

  40. Sani NS, Malek NANN, Jemon K, Kadir MRA, and Hamdan H (2017) Effect of mass concentration on bioactivity and cell viability of calcined silica aerogel synthesized from rice husk ash as silica source. Journal of Sol-Gel Science and Technology 82(1):120–132

    Google Scholar 

  41. Sani NS, Malek NANN, Jemon K, Kadir MRA, and Hamdan H (2020) In vitro bioactivity and osteoblast cell viability studies of hydroxyapatite-incorporated silica aerogel. Journal of Sol-Gel Science and Technology 96(1):166–177

    Google Scholar 

  42. Sani NS, Synthesis and characterization of hydroxyapatite incorporated silica aerogel for medical application, in Biomedical Engineering. 2017, Universiti Teknologi Malaysia.

    Google Scholar 

  43. Antoniac IV, Antoniac A, Vasile E, Tecu C, Fosca M, Yankova VG, and Rau JV (2021) In vitro characterization of novel nanostructured collagen-hydroxyapatite composite scaffolds doped with magnesium with improved biodegradation rate for hard tissue regeneration. Bioactive Materials 6(10):3383–3395

    Google Scholar 

  44. Razavi M and Huang Y (2020) Effect of hydroxyapatite (HA) nanoparticles shape on biodegradation of Mg/HA nanocomposites processed by high shear solidification/equal channel angular extrusion route. Materials Letters 267:127541

    Google Scholar 

  45. Liu Y, Gu J, and Fan D (2020) Fabrication of high-strength and porous hybrid scaffolds based on nano-hydroxyapatite and human-like collagen for bone tissue regeneration. Polymers 12(1):61

    Google Scholar 

  46. Pagliaro M, Ciriminna R, Yusuf M, Eskandarinezhad S, Wani IA, Ghahremani M, and Nezhad ZR (2021) Application of nanocellulose composites in the environmental engineering as a catalyst, flocculants, and energy storages: A review. Journal of Composites and Compounds 3(7):114–128

    Google Scholar 

  47. Li Q, Wu Y, Fang R, Lei C, Li Y, Li B, Pei Y, and Luo X (2021) Application of Nanocellulose as particle stabilizer in food Pickering emulsion: Scope, Merits and challenges. Trends in Food Science & Technology

    Google Scholar 

  48. Zhang Q, Zhang L, Wu W, and Xiao H (2020) Methods and applications of nanocellulose loaded with inorganic nanomaterials: A review. Carbohydrate polymers 229:115454

    Google Scholar 

  49. Anirudhan T and Rejeena S (2015) Photocatalytic degradation of eosin yellow using poly (pyrrole-co-aniline)-coated TiO2/nanocellulose composite under solar light irradiation. Journal of Materials 2015:1–11

    Google Scholar 

  50. Abraham E, Elbi P, Deepa B, Jyotishkumar P, Pothen L, Narine S, and Thomas S (2012) X-ray diffraction and biodegradation analysis of green composites of natural rubber/nanocellulose. Polymer Degradation and Stability 97(11):2378–2387

    Google Scholar 

  51. Ong HL, Villagracia AR, Owi WT, Sam ST, and Akil HM (2020) Revealing the Water Resistance, Thermal and Biodegradation Properties of Citrus aurantifolia Crosslinked Tapioca Starch/Nanocellulose Bionanocomposites. Journal of Polymers and the Environment 28(12):3256–3269

    Google Scholar 

  52. Mondal S, Nanocellulose reinforced polymer nanocomposites for sustainable packaging of foods, cosmetics, and pharmaceuticals, in Sustainable nanocellulose and nanohydrogels from natural sources. 2020, Elsevier. p. 237–253.

    Google Scholar 

  53. Favi PM, Ospina SP, Kachole M, Gao M, Atehortua L, and Webster TJ (2016) Preparation and characterization of biodegradable nano hydroxyapatite–bacterial cellulose composites with well-defined honeycomb pore arrays for bone tissue engineering applications. Cellulose 23(2):1263–1282

    Google Scholar 

  54. Luz EPCG, Chaves PHS, Vieira LdAP, Ribeiro SF, de Fátima Borges M, Andrade FK, Muniz CR, Infantes-Molina A, Rodríguez-Castellón E, and de Freitas Rosa M (2020) In vitro degradability and bioactivity of oxidized bacterial cellulose-hydroxyapatite composites. Carbohydrate polymers 237:116174

    Google Scholar 

  55. Jaiswal S, Dubey A, and Lahiri D (2020) The influence of bioactive hydroxyapatite shape and size on the mechanical and biodegradation behaviour of magnesium based composite. Ceramics International 46(17):27205–27218

    Google Scholar 

  56. Hench LL (2006) The story of Bioglass®. Journal of Materials Science: Materials in Medicine 17(11):967–978

    Google Scholar 

  57. Zadpoor AA (2014) Relationship between in vitro apatite-forming ability measured using simulated body fluid and in vivo bioactivity of biomaterials. Materials Science and Engineering: C 35:134–143

    Google Scholar 

  58. Kim H-M, Himeno T, Kawashita M, Kokubo T, and Nakamura T (2004) The mechanism of biomineralization of bone-like apatite on synthetic hydroxyapatite: an in vitro assessment. Journal of the Royal Society Interface 1(1):17–22

    Google Scholar 

  59. Pereira MM and Hench LL (1996) Mechanisms of hydroxyapatite formation on porous gel-silica substrates. Journal of Sol-Gel Science and Technology 7(1):59–68

    Google Scholar 

  60. Toro RG, Adel AM, de Caro T, Federici F, Cerri L, Bolli E, Mezzi A, Barbalinardo M, Gentili D, and Cavallini M (2021) Evaluation of Long–Lasting Antibacterial Properties and Cytotoxic Behavior of Functionalized Silver-Nanocellulose Composite. Materials 14(15):4198

    Google Scholar 

  61. Pandey VK, Upadhyay SN, Niranjan K, and Mishra PK (2020) Antimicrobial biodegradable chitosan-based composite Nano-layers for food packaging. International journal of biological macromolecules 157:212–219

    Google Scholar 

  62. de Souza AG, Dos Santos NMA, da Silva Torin RF, and dos Santos Rosa D (2020) Synergic antimicrobial properties of Carvacrol essential oil and montmorillonite in biodegradable starch films. International Journal of Biological Macromolecules 164:1737–1747

    Google Scholar 

  63. Motelica L, Ficai D, Oprea O, Ficai A, Trusca R-D, Andronescu E, and Holban AM (2021) Biodegradable Alginate Films with ZnO Nanoparticles and Citronella Essential Oil—A Novel Antimicrobial Structure. Pharmaceutics 13(7):1020

    Google Scholar 

  64. Lee C-H, Liu K-S, Cheng C-W, Chan E-C, Hung K-C, Hsieh M-J, Chang S-H, Fu X, Juang J-H, and Hsieh I-C (2020) Codelivery of sustainable antimicrobial agents and platelet-derived growth factor via biodegradable nanofibers for repair of diabetic infectious wounds. ACS Infectious Diseases 6(10):2688–2697

    Google Scholar 

  65. Depan D, Biodegradable polymeric nanocomposites: advances in biomedical applications. 2015: CRC Press.

    Google Scholar 

  66. Spence K, Habibi Y, and Dufresne A, Nanocellulose-based composites, in Cellulose fibers: bio-and nano-polymer composites. 2011, Springer. p. 179–213.

    Google Scholar 

  67. Siqueira G, Bras J, and Dufresne A (2010) Cellulosic bionanocomposites: a review of preparation, properties and applications. Polymers 2(4):728–765

    Google Scholar 

  68. Ben Shalom T, Nevo Y, Leibler D, Shtein Z, Azerraf C, Lapidot S, and Shoseyov O (2019) Cellulose nanocrystals (CNCs) induced crystallization of polyvinyl alcohol (PVA) super performing nanocomposite films. Macromolecular bioscience 19(3):1800347

    Google Scholar 

  69. Richardson JJ, Björnmalm M, and Caruso F (2015) Technology-driven layer-by-layer assembly of nanofilms. Science 348(6233)

    Google Scholar 

  70. Doblaré M, Garcıa J, and Gómez M (2004) Modelling bone tissue fracture and healing: a review. Engineering Fracture Mechanics 71(13–14):1809–1840

    Google Scholar 

  71. Albrektsson T and Johansson C (2001) Osteoinduction, osteoconduction and osseointegration. European spine journal 10(2):S96–S101

    Google Scholar 

  72. Wei G and Ma PX (2004) Structure and properties of nano-hydroxyapatite/polymer composite scaffolds for bone tissue engineering. Biomaterials 25(19):4749–4757

    Google Scholar 

  73. Khan NI, Ijaz K, Zahid M, Khan AS, Kadir MRA, Hussain R, Darr JA, and Chaudhry AA (2015) Microwave assisted synthesis and characterization of magnesium substituted calcium phosphate bioceramics. Materials Science and Engineering: C 56:286–293

    Google Scholar 

  74. Precnerová M, Bodišová K, Frajkorová F, Galusková D, Nováková ZV, Vojtaššák J, Lenčéš Z, and Šajgalík P (2015) In vitro bioactivity of silicon nitride–hydroxyapatite composites. Ceramics International 41(6):8100–8108

    Google Scholar 

  75. Rodríguez-Lorenzo LM and Gross KA (2004) Encapsulation of hydroxyapatite microspheres with fluorapatite using a diffusion process. Journal of the American Ceramic Society 87(5):814–818

    Google Scholar 

  76. Veiderma M, Tõnsuaadu K, Knubovets R, and Peld M (2005) Impact of anionic substitutions on apatite structure and properties. Journal of Organometallic Chemistry 690(10):2638–2643

    Google Scholar 

  77. Ravarian R, Moztarzadeh F, Hashjin MS, Rabiee S, Khoshakhlagh P, and Tahriri M (2010) Synthesis, characterization and bioactivity investigation of bioglass/hydroxyapatite composite. Ceramics International 36(1):291–297

    Google Scholar 

  78. Iqbal N, Kadir MA, Iqbal S, Abd Razak SI, Rafique MS, Bakhsheshi-Rad H, Idris MH, Khattak M, Raghavendran H, and Abbas A (2016) Nano-hydroxyapatite reinforced zeolite ZSM composites: A comprehensive study on the structural and in vitro biological properties. Ceramics International 42(6):7175–7182

    Google Scholar 

  79. Jongwattanapisan P, Charoenphandhu N, Krishnamra N, Thongbunchoo J, Tang I-M, Hoonsawat R, Smith SM, and Pon-On W (2011) In vitro study of the SBF and osteoblast-like cells on hydroxyapatite/chitosan–silica nanocomposite. Materials Science and Engineering: C 31(2):290–299

    Google Scholar 

  80. Lv Q, Nair L, and Laurencin CT (2009) Fabrication, characterization, and in vitro evaluation of poly (lactic acid glycolic acid)/nano-hydroxyapatite composite microsphere-based scaffolds for bone tissue engineering in rotating bioreactors. Journal of Biomedical Materials Research Part A: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials 91(3):679–691

    Google Scholar 

  81. Im O, Li J, Wang M, Zhang LG, and Keidar M (2012) Biomimetic three-dimensional nanocrystalline hydroxyapatite and magnetically synthesized single-walled carbon nanotube chitosan nanocomposite for bone regeneration. International journal of nanomedicine 7:2087

    Google Scholar 

  82. Porter AE, Buckland T, Hing K, Best SM, and Bonfield W (2006) The structure of the bond between bone and porous silicon-substituted hydroxyapatite bioceramic implants. Journal of Biomedical Materials Research Part A: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials 78(1):25–33

    Google Scholar 

  83. Heinemann S, Heinemann C, Wenisch S, Alt V, Worch H, and Hanke T (2013) Calcium phosphate phases integrated in silica/collagen nanocomposite xerogels enhance the bioactivity and ultimately manipulate the osteoblast/osteoclast ratio in a human co-culture model. Acta biomaterialia 9(1):4878–4888

    Google Scholar 

  84. Guan F, Ma S, Shi X, Ma X, Chi L, Liang S, Cui Y, Wang Z, Yao N, and Guan S (2014) Biocompatibility of nano-hydroxyapatite/Mg-Zn-Ca alloy composite scaffolds to human umbilical cord mesenchymal stem cells from Wharton’s jelly in vitro. Science China Life Sciences 57(2):181–187

    Google Scholar 

  85. Kang E-S, Kim D-S, Suhito IR, Lee W, Song I, and Kim T-H (2018) Two-dimensional material-based bionano platforms to control mesenchymal stem cell differentiation. Biomaterials research 22(1):1–12

    Google Scholar 

  86. Ignat S-R, Lazăr AD, Şelaru A, Samoilă I, Vlăsceanu GM, Ioniţă M, Radu E, Dinescu S, and Costache M (2019) Versatile biomaterial platform enriched with graphene oxide and carbon nanotubes for multiple tissue engineering applications. International journal of molecular sciences 20(16):3868

    Google Scholar 

  87. Prabhakaran MP, Mobarakeh LG, Kai D, Karbalaie K, Nasr-Esfahani MH, and Ramakrishna S (2014) Differentiation of embryonic stem cells to cardiomyocytes on electrospun nanofibrous substrates. Journal of Biomedical Materials Research Part B: Applied Biomaterials 102(3):447–454

    Google Scholar 

  88. Ding K, Wang Y, Wang H, Yuan L, Tan M, Shi X, Lyu Z, Liu Y, and Chen H (2014) 6-O-sulfated chitosan promoting the neural differentiation of mouse embryonic stem cells. ACS applied materials & interfaces 6(22):20043–20050

    Google Scholar 

  89. Jan E and Kotov NA (2007) Successful differentiation of mouse neural stem cells on layer-by-layer assembled single-walled carbon nanotube composite. Nano letters 7(5):1123–1128

    Google Scholar 

  90. Zhang Q, Hubenak J, Iyyanki T, Alred E, Turza KC, Davis G, Chang EI, Branch-Brooks CD, Beahm EK, and Butler CE (2015) Engineering vascularized soft tissue flaps in an animal model using human adipose–derived stem cells and VEGF+ PLGA/PEG microspheres on a collagen-chitosan scaffold with a flow-through vascular pedicle. Biomaterials 73:198–213

    Google Scholar 

  91. Eke G, Mangir N, Hasirci N, MacNeil S, and Hasirci V (2017) Development of a UV crosslinked biodegradable hydrogel containing adipose derived stem cells to promote vascularization for skin wounds and tissue engineering. Biomaterials 129:188–198

    Google Scholar 

  92. Blaško J, Szekiova E, Slovinska L, Kafka J, and Cizkova D (2017) Axonal outgrowth stimulation after alginate/mesenchymal stem cell therapy in injured rat spinal cord. Acta Neurobiol Exp (Wars) 77(4):337–350

    Google Scholar 

  93. Ghaedi M, Soleimani M, Shabani I, Duan Y, and Lotfi A (2012) Hepatic differentiation from human mesenchymal stem cells on a novel nanofiber scaffold. Cellular and Molecular Biology Letters 17(1):89–106

    Google Scholar 

  94. Namgung S, Baik KY, Park J, and Hong S (2011) Controlling the growth and differentiation of human mesenchymal stem cells by the arrangement of individual carbon nanotubes. ACS nano 5(9):7383–7390

    Google Scholar 

  95. Spadaccio C, Rainer A, Trombetta M, Vadalá G, Chello M, Covino E, Denaro V, Toyoda Y, and Genovese JA (2009) Poly-L-lactic acid/hydroxyapatite electrospun nanocomposites induce chondrogenic differentiation of human MSC. Annals of biomedical engineering 37(7):1376–1389

    Google Scholar 

  96. D’Angelo F, Armentano I, Cacciotti I, Tiribuzi R, Quattrocelli M, Del Gaudio C, Fortunati E, Saino E, Caraffa A, and Cerulli GG (2012) Tuning multi/pluri-potent stem cell fate by electrospun poly (L-lactic acid)-calcium-deficient hydroxyapatite nanocomposite mats. Biomacromolecules 13(5):1350–1360

    Google Scholar 

  97. Yang K, Park E, Lee JS, Kim IS, Hong K, Park KI, Cho SW, and Yang HS (2015) Biodegradable nanotopography combined with neurotrophic signals enhances contact guidance and neuronal differentiation of human neural stem cells. Macromolecular bioscience 15(10):1348–1356

    Google Scholar 

  98. Kam NWS, Jan E, and Kotov NA (2009) Electrical stimulation of neural stem cells mediated by humanized carbon nanotube composite made with extracellular matrix protein. Nano letters 9(1):273–278

    Google Scholar 

  99. Worthington KS, Green BJ, Rethwisch M, Wiley LA, Tucker BA, Guymon CA, and Salem AK (2016) Neuronal differentiation of induced pluripotent stem cells on surfactant templated chitosan hydrogels. Biomacromolecules 17(5):1684–1695

    Google Scholar 

  100. Dhert W, Thomsen P, Blomgren A, Esposito M, Ericson L, and Verbout A (1998) Integration of press-fit implants in cortical bone: A study on interface kinetics. Journal of Biomedical Materials Research: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and the Australian Society for Biomaterials 41(4):574–583

    Google Scholar 

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, Malaysia

    Juan Matmin

  2. Department of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, Malaysia

    Nik Ahmad Nizam Nik Malek

  3. Office of Deputy Vice-Chancellor (Research & Innovation), Universiti Teknologi Malaysia, Johor Bahru, Malaysia

    Nor Suriani Sani

Authors
  1. Juan Matmin
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  2. Nik Ahmad Nizam Nik Malek
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  3. Nor Suriani Sani
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Corresponding author

Correspondence to Juan Matmin .

Editor information

Editors and Affiliations

  1. Chemistry Department, Al-Azhar University, Assiut, Egypt

    Gomaa A. M. Ali

  2. Vice President of Advanced Material Research,, Stanley Black & Decker, Inc, Connecticut, USA

    Abdel Salam H. Makhlouf

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Matmin, J., Malek, N.A.N.N., Sani, N.S. (2023). Biodegradable Inorganic Nanocomposites. In: Ali, G.A.M., Makhlouf, A.S.H. (eds) Handbook of Biodegradable Materials. Springer, Cham. https://doi.org/10.1007/978-3-031-09710-2_23

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