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Imaging of Pediatric Traumatic and Nontraumatic Brain Emergencies

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Atlas of Emergency Imaging from Head-to-Toe

Abstract

Neuroimaging plays a central role in the initial diagnosis, follow-up, prognosis, and decision-making for various acute intracranial pathologies in children. Whereas the rarity of several of these conditions in children, poorly understood natural histories, limited representation in the literature, nonspecificity of clinical signs, and heterogeneity of treatment responses make frequent neuroimaging desirable, this has to be counterbalanced against associated risks and costs. Considerations which are usually relatively straightforward and minor in adult patients can lead to substantial morbidity and anxiety in pediatric hospitals, for instance, extravasation of even a small amount of IV contrast agent can result in limb edema and/or compartment syndrome. Imaging examinations in small children often require general anesthesia. Similarly, procedures that entail ionizing radiation, i.e., CT and digital subtraction angiography, necessitate diligent justification with dialogue between the neuroradiologist and the clinical team, with every effort made to ensure that call-back examinations are eliminated. This also implies that alternative imaging be performed when feasible for obtaining similar information, for instance, awake bedside transcranial Doppler or alternative fast sequence MR protocol under adequate clinical indications, to assess ventricular size in infants. In yet other cases, established adult pipelines for neuroimaging are not necessarily suitable in children, such as multiphasic CTA for adult stroke patients for triaging of endovascular therapy. Lastly, the availability of pediatric-trained nurses and technologists in a radiology department is fundamental to minimizing morbidity and obtaining high-quality images and for the care of pediatric patients undergoing interventional procedures.

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References

  1. Exo J, Smith C, Smith R, Bell M. Emergency treatment options for pediatric traumatic brain injury. Pediatr Health. 2009;3(6):533–41.

    Article  CAS  Google Scholar 

  2. Case ME, Graham MA, Handy TC, Jentzen JM, Monteleone JA. National Association of medical examiners ad hoc committee on Shaken Baby syndrome. Position paper on fatal abusive head injuries in infants and young children. Am J Forensic Med Pathol. 2001;22(2):112–22.

    Article  CAS  PubMed  Google Scholar 

  3. Kumpulainen V, Lehtola SJ, Tuulari JJ, Silver E, Copeland A, Korja R, et al. Prevalence and risk factors of incidental findings in brain MRIs of healthy neonates – the FinnBrain birth cohort study. Front Neurol. 2020;10:1347.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Poussaint TY, Moeller KK. Imaging of pediatric head trauma. Neuroimaging Clin N Am. 2002;12(2):271–94.

    Article  PubMed  Google Scholar 

  5. Rooks VJ, Eaton JP, Ruess L, Petermann GW, Keck-Wherley J, Pedersen RC. Prevalence and evolution of intracranial hemorrhage in asymptomatic term infants. Am J Neuroradiol. 2008;29(6):1082–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Looney CB, Smith JK, Merck LH, Wolfe HM, Chescheir NC, Hamer RM, et al. Intracranial hemorrhage in asymptomatic neonates: prevalence on MR images and relationship to obstetric and neonatal risk factors. Radiology. 2007;242(2):535–41.

    Article  PubMed  Google Scholar 

  7. Chaturvedi A, Chaturvedi A, Stanescu AL, Blickman JG, Meyers SP. Mechanical birth-related trauma to the neonate: an imaging perspective. Insights Imaging. 2018;9(1):103–18.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Popernack ML, Gray N, Reuter-Rice K. Moderate-to-severe traumatic brain injury in children: complications and rehabilitation strategies. J Pediatr Health Care. 2015;29(3):e1–7.

    Article  PubMed  Google Scholar 

  9. Wang H, Zhou Y, Liu J, Ou L, Han J, Xiang L. Traumatic skull fractures in children and adolescents: a retrospective observational study. Injury. 2018;49(2):219–25.

    Article  CAS  PubMed  Google Scholar 

  10. Armin SS, Colohan ART, Zhang JH. Vasospasm in traumatic brain injury. Acta Neurochir Suppl. 2008;104(13):421–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Paul AR, Adamo MA. Non-accidental trauma in pediatric patients: a review of epidemiology, pathophysiology, diagnosis and treatment. Transl Pediatr. 2014;3(3):195–207.

    PubMed  PubMed Central  Google Scholar 

  12. Vezina G. Assessment of the nature and age of subdural collections in nonaccidental head injury with CT and MRI. Pediatr Radiol. 2009;39(6):586–90.

    Article  PubMed  Google Scholar 

  13. Gunda D, Cornwell BO, Dahmoush HM, Jazbeh S, Alleman AM. Pediatric central nervous system imaging of nonaccidental trauma: beyond subdural hematomas. Radiographics. 2018;39(1):213–28.

    Article  PubMed  Google Scholar 

  14. Orman G, Kralik SF, Meoded A, Desai N, Risen S, Huisman TAGM. MRI findings in pediatric abusive head trauma: a review. J Neuroimaging. 2020;30(1):15–27.

    Article  PubMed  Google Scholar 

  15. Silvera VM, Danehy AR, Newton AW, Stamoulis C, Carducci C, Grant PE, et al. Retroclival collections associated with abusive head trauma in children. Pediatr Radiol. 2014;44(4):621–31.

    Article  Google Scholar 

  16. Wright JN. CNS injuries in abusive head trauma. AJR Am J Roentgenol. 2017;208(5):991–1001.

    Article  PubMed  Google Scholar 

  17. Khan NR, Fraser BD, Nguyen V, Moore K, Boop S, Vaughn BN, et al. Pediatric abusive head trauma and stroke. J Neurosurg Pediatr. 2017;20(2):183–90.

    Article  PubMed  Google Scholar 

  18. Lo WD, Lee J, Rusin J, Perkins E, Roach ES. Intracranial hemorrhage in children: an evolving Spectrum. Arch Neurol. 2008;65(12):1629–33.

    Article  PubMed  Google Scholar 

  19. Cole L, Dewey D, Letourneau N, Kaplan BJ, Chaput K, Gallagher C, et al. Clinical characteristics, risk factors, and outcomes associated with neonatal hemorrhagic stroke: a population-based case-control study. JAMA Pediatr. 2017;171(3):230–8.

    Article  PubMed  Google Scholar 

  20. El-Ghanem M, Kass-Hout T, Kass-Hout O, Alderazi YJ, Amuluru K, Al-Mufti F, et al. Arteriovenous malformations in the pediatric population: review of the existing literature. Intervent Neurol. 2016;5(3–4):218–25.

    Article  Google Scholar 

  21. Walcott BP, Smith ER, Scott RM, Orbach DB. Pial arteriovenous fistulae in pediatric patients: associated syndromes and treatment outcome. J NeuroIntervent Surg. 2013;5(1):10–4.

    Article  Google Scholar 

  22. Jhaveri A, Amirabadi A, Dirks P, Kulkarni AV, Shroff MM, Shkumat N, et al. Predictive value of MRI in diagnosing brain AVM recurrence after angiographically documented exclusion in children. AJNR Am J Neuroradiol. 2019;40(7):1227–35.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Päivi K-P, Mika N, Hanna L, Riku K, Jussi N, Aki L, et al. De novo and recurrent aneurysms in pediatric patients with cerebral aneurysms. Stroke. 2013;44(5):1436–9.

    Article  Google Scholar 

  24. Bisson D-A, Dirks P, Amirabadi A, Shroff MM, Krings T, Pereira VM, et al. Unruptured intracranial aneurysms in children: 18 years’ experience in a tertiary care pediatric institution. J Neurosurg Pediatr. 2019;24(2):184–9.

    Article  PubMed  Google Scholar 

  25. Dmytriw AA, Bisson D-A, Phan K, Amirabadi A, Branson H, Dirks PB, et al. Locations, associations and temporal evolution of intracranial arterial infundibular dilatations in children. J Neurointervent Surg. 2020;12(5):495–8.

    Article  Google Scholar 

  26. Krings T, Geibprasert S, terBrugge KG. Pathomechanisms and treatment of pediatric aneurysms. Childs Nerv Syst. 2010;26(10):1309–18.

    Article  PubMed  Google Scholar 

  27. Tsze DS, Valente JH. Pediatric stroke: a review. Emerg Med Int. 2011; [cited 2020 Apr 25]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255104/

  28. Mirsky DM, Beslow LA, Amlie-Lefond C, Krishnan P, Laughlin S, Lee S, et al. Pathways for neuroimaging of childhood stroke. Pediatr Neurol. 2017;69:11–23.

    Article  PubMed  Google Scholar 

  29. Bhatia K, Kortman H, Blair C, Parker G, Brunacci D, Ang T, et al. Mechanical thrombectomy in pediatric stroke: systematic review, individual patient data meta-analysis, and case series. J Neurosurg Pediatr. 2019:1–14.

    Google Scholar 

  30. Grunt S, Wingeier K, Wehrli E, Boltshauser E, Capone A, Fluss J, et al. Cerebral sinus venous thrombosis in Swiss children. Dev Med Child Neurol. 2010;52(12):1145–50.

    Article  PubMed  Google Scholar 

  31. Rollins N, Ison C, Reyes T, Chia J. Cerebral MR venography in children: comparison of 2D time-of-flight and gadolinium-enhanced 3D gradient-Echo techniques. Radiology. 2005;235(3):1011–7.

    Article  PubMed  Google Scholar 

  32. Triulzi F, Doneda C, Parazzini C. Neuroimaging of pediatric brain infections. Expert Rev Anti-Infect Ther. 2011;9(6):737–51.

    Article  PubMed  Google Scholar 

  33. Okanishi T, Yamamoto H, Hosokawa T, Ando N, Nagayama Y, Hashimoto Y, et al. Diffusion-weighted MRI for early diagnosis of neonatal herpes simplex encephalitis. Brain and Development. 2015;37(4):423–31.

    Article  PubMed  Google Scholar 

  34. Jayaraman K, Rangasami R, Chandrasekharan A. Magnetic resonance imaging findings in viral encephalitis: a pictorial essay. J Neurosci Rural Pract. 2018;9(4):556–60.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Park JY, Ko KO, Lim JW, Cheon EJ, Yoon JM, Kim HJ. A pediatric case of Bickerstaff’s brainstem encephalitis. Korean J Pediatr. 2014;57(12):542–5.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Oliveira CR, Morriss MC, Mistrot JG, Cantey JB, Doern CD, Sánchez PJ. Brain magnetic resonance imaging of infants with bacterial meningitis. J Pediatr. 2014;165(1):134–9.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Pienaar M, Andronikou S, van Toorn R. MRI to demonstrate diagnostic features and complications of TBM not seen with CT. Childs Nerv Syst ChNS Off J Int Soc Pediatr Neurosurg. 2009;25(8):941–7.

    Article  Google Scholar 

  38. Grant PE, Yu D. Acute injury to the immature brain with hypoxia with or without hypoperfusion. Radiol Clin N Am. 2006;44(1):63–77, viii

    Article  PubMed  Google Scholar 

  39. Huang BY, Castillo M. Hypoxic-ischemic brain injury: imaging findings from birth to adulthood. Radiographics. 2008;28(2):417–39.

    Article  PubMed  Google Scholar 

  40. Tardieu M, Banwell B, Wolinsky JS, Pohl D, Krupp LB. Consensus definitions for pediatric MS and other demyelinating disorders in childhood: table. Neurology. 2016;87(9 Suppl 2):S8–11.

    Article  PubMed  Google Scholar 

  41. Banwell B, Arnold DL, Tillema J-M, Rocca MA, Filippi M, Weinstock-Guttman B, et al. MRI in the evaluation of pediatric multiple sclerosis. Neurology. 2016;87(9 Suppl 2):S88–96.

    Article  PubMed  Google Scholar 

  42. Gibbs WN, Kreidie MA, Kim RC, Hasso AN. Acute hemorrhagic leukoencephalitis: neuroimaging features and neuropathologic diagnosis. J Comput Assist Tomogr. 2005;29(5):689–93.

    Article  PubMed  Google Scholar 

  43. Reis E, Coolen T, Lolli V. MRI findings in acute hyperammonemic encephalopathy: three cases of different etiologies. J Belg Soc Radiol. 2020;104(1):9.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Abbott R, Silber E, Felber J, Ekpo E. Osmotic demyelination syndrome. BMJ. 2005;331(7520):829–30.

    Article  PubMed  PubMed Central  Google Scholar 

  45. Pillai A, Rajeev K, Unnikrishnan M. Surgical management of a pial arteriovenous fistula with giant varix in an infant. Neurol India. 2006;54(4):434–6.

    Article  PubMed  Google Scholar 

  46. Madsen PJ, Lang S-S, Pisapia JM, Storm PB, Hurst RW, Heuer GG. An institutional series and literature review of pial arteriovenous fistulas in the pediatric population: clinical article. J Neurosurg Pediatr. 2013;12(4):344–50.

    Article  PubMed  Google Scholar 

  47. Morales H, Jones BV, Leach JL, Abruzzo TA. Documented development of a dural arteriovenous fistula in an infant subsequent to sinus thrombosis: case report and review of the literature. Neuroradiology. 2010;52(3):225–9.

    Article  PubMed  Google Scholar 

  48. Hoang S, Choudhri O, Edwards M, Guzman R. Vein of Galen malformation. Neurosurg Focus. 2009;27(5):E8.

    Article  PubMed  Google Scholar 

  49. Bhatia K, Mendes Pereira V, Krings T, Ter Brugge K, Kortman H, Dirks P et al. Factors contributing to major neurological complications from vein of Galen malformation embolization. JAMA Neurol. 2020.

    Google Scholar 

  50. Lasjaunias P. Vein of Galen aneurysmal malformation. In: Lasjaunias P, editor. Vascular diseases in neonates, infants and children: interventional neuroradiology management [Internet]. Berlin/Heidelberg: Springer; 1997. p. 67–202. https://doi.org/10.1007/978-3-662-10740-9_2. [cited 2020 May 27].

    Chapter  Google Scholar 

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Muthusami, P., Dmytriw, A.A., Shroff, M.M. (2022). Imaging of Pediatric Traumatic and Nontraumatic Brain Emergencies. In: Patlas, M.N., Katz, D.S., Scaglione, M. (eds) Atlas of Emergency Imaging from Head-to-Toe. Springer, Cham. https://doi.org/10.1007/978-3-030-92111-8_44

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  • DOI: https://doi.org/10.1007/978-3-030-92111-8_44

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