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Modeling with Biomarkers: Nitrosamines and Phytochemical Protection

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Biomarkers in Toxicology

Abstract

Humans may be exposed to nitrosamines through agricultural pesticides, cosmetics, pharmaceutical preparations, and food preservatives, which are all known to be carcinogenic in the environment. In laboratory animals, nitrosamine chemicals were classed as carcinogenic. The liver is the organ that deals with oxidative stress the most. As a result, prolonged liver damage can lead to major medical problems including fibrosis, which can progress to cirrhosis and liver cancer. Even though the human body can preserve itself within certain limits, the increasing rate of oxidative stress may necessitate the use of external natural antioxidant sources. A large range of natural antioxidants have been shown to have beneficial impacts on human health as well as disease prevention. Specific elements in these plants can also serve as antioxidants; Substances that can either stop or slow down the oxidation process. The purpose of this chapter is to investigate the protective effects of different phytochemicals against the hazardous molecules, nitrosamines.

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Abdur-Rahman, M., Shams-Eldin, E. (2022). Modeling with Biomarkers: Nitrosamines and Phytochemical Protection. In: Patel, V.B., Preedy, V.R., Rajendram, R. (eds) Biomarkers in Toxicology. Biomarkers in Disease: Methods, Discoveries and Applications. Springer, Cham. https://doi.org/10.1007/978-3-030-87225-0_61-1

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  • DOI: https://doi.org/10.1007/978-3-030-87225-0_61-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-87225-0

  • Online ISBN: 978-3-030-87225-0

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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