Abstract
Biodegradation is a process of degradation and deterioration of material due to exposure to microorganisms aerobic and anaerobic processes. Biodegradable polymers have been used widely in tissue engineering, and their application varies from bone tissue, epithelium, vascular, and cardiac tissue. This is important to treat patients by mimicking cardiac tissue’s extracellular matrix structure, which helps it regenerate the new cell and degrade after some time. Some polymers are biocompatible, are nontoxic, and have good mechanical integrity and thermal plasticity but longer degradable periods. This chapter will highlight the various types of polymers used in the cardiac tissue scaffolds, biodegradable properties of the polymers, and cost-effective synthesis methods.
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Abbreviations
- AMSF:
-
Acid-modified silk fibroin
- BDP:
-
Biodegradable polymer
- BMSC:
-
Bone marrow mesenchymal stem cell
- CVD:
-
Cardiovascular disease
- ECM:
-
Extracellular matrix
- F6P:
-
Fructose-6-phosphate
- FDM :
-
Fused deposition modeling
- HA:
-
Hyaluronic acid
- hiPSC-CM :
-
Human-induced pluripotent stem cell-derived cardiomyocyte
- hPSC:
-
Human pluripotent stem cell
- LV:
-
Left ventricular
- MI:
-
Myocardial infarction
- MTE :
-
Myocardial tissue engineering
- SF:
-
Silk fibroin
- TE:
-
Tissue engineering
- Tg:
-
Glass transition temperature
- Tm:
-
Melting temperature
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Yaacob, A., Jamaludin, N.S. (2022). Biodegradable Polymers for Cardiac Tissue Engineering. In: Ali, G.A.M., Makhlouf, A.S.H. (eds) Handbook of Biodegradable Materials. Springer, Cham. https://doi.org/10.1007/978-3-030-83783-9_44-1
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