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Peritoneal Structure and Changes as a Dialysis Membrane After Peritoneal Dialysis

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Nolph and Gokal's Textbook of Peritoneal Dialysis

Abstract

In this chapter, the purpose of the authors and editors is to review and concentrate the incomparable information included in the 3rd edition of this Textbook by L. Gotloib, maintaining the most significant messages relative to mesothelial cell role in the peritoneal membrane. For more profound knowledge in this particular field, the reader is referred to the complete chapter published in the 3rd edition of this Textbook, as Gotloib as the sole author.

Our contribution will be to specifically add the changes that the structure of the membrane suffers during peritoneal dialysis treatment in each of its components, including the epithelial-to-mesenchymal transition of mesothelial cells, angiogenesis/vasculopathy and interstitial fibrosis/sclerosis, as well as the connections between these processes, to give the clinician an active view of all these components and their relationship with functional changes.

L. Gotloib: deceased.

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Acknowledgments

To Lázaro Gotloib in memoriam for having built the basis of this chapter, giving us the opportunity to follow and extend his remarkable message, by completing the knowledge published after his disappearance.

To Dr. José Jimenez-Heffernan, outstanding pathologist at Hospital de La Princesa, in Madrid, who has helped us to understand the pathology of the peritoneum at different stages of disease. Part of the figures in this chapter comes from his laboratory.

To Dr. Guadalupe Gonzalez, peritoneal researcher at IdiPAZ and CBM, who has helped us to manage this chapter.

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Authors and Affiliations

  1. Hospital Universitario La Paz, IdiPAZ, Universidad Autonoma de Madrid, Madrid, Spain

    Rafael Selgas

  2. Department of Anatomy, Showa University School of Medicine, Tokyo, Japan

    Kazuho Honda

  3. Centro de Biologia Molecular “Severo Ochoa”, Madrid, Spain

    Manuel López-Cabrera

  4. Juntendo University, Tokyo, Japan

    Chieko Hamada

  5. Department of Nephrology, Ha’Emek Medical Center, Afula, Israel

    Lázaro Gotloib

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  1. Rafael Selgas
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  2. Kazuho Honda
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  3. Manuel López-Cabrera
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  4. Chieko Hamada
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  5. Lázaro Gotloib
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Corresponding author

Correspondence to Rafael Selgas .

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Editors and Affiliations

  1. University of Missouri, Columbia, MO, USA

    Ramesh Khanna

  2. Dept. Medicine Div. Nephrology, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands

    Raymond T. Krediet

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Selgas, R., Honda, K., López-Cabrera, M., Hamada, C., Gotloib, L. (2023). Peritoneal Structure and Changes as a Dialysis Membrane After Peritoneal Dialysis. In: Khanna, R., Krediet, R.T. (eds) Nolph and Gokal's Textbook of Peritoneal Dialysis. Springer, Cham. https://doi.org/10.1007/978-3-030-62087-5_39

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  • DOI: https://doi.org/10.1007/978-3-030-62087-5_39

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