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History of Peritoneal Dialysis

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Nolph and Gokal's Textbook of Peritoneal Dialysis
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Abstract

The concept of the uremic syndrome caused by blood and tissue accumulation of toxic substances normally excreted in the urine was an established idea in the middle of nineteenth century. In the late 1800s, renal insufficiency and concurrent uremic intoxication were treated only by simple and ineffective measures such as blood-letting, dietary changes, digitalis, infusion of normal saline followed by forced diuresis, purgation, and diaphoresis. The period of time surrounding the beginning of the twentieth century was marked by intense research and growth in scientific knowledge that allowed the birth of clinical dialysis, a lifesaving therapy for patients with renal failure.

The following items will be discussed: The discovery of principles of dialysis; peritoneal permeability and the peritoneal membrane; the birth of clinical dialysis; first attempts at peritoneal dialysis; early experience in peritoneal dialysis; the modern era of peritoneal dialysis; first step in long-term peritoneal dialysis; the Tenckhoff catheter; the growth of and disappointment with intermittent peritoneal dialysis; continuous ambulatory peritoneal dialysis; CAPD with plastic bags; the Y-set and “flush before fill” system; automated peritoneal dialysis; peritoneal dialysis catheters; peritoneal dialysis solutions; current state of peritoneal dialysis.

This contribution was authored by D. Negoi and K.D. Nolph in the previous edition.

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Negoi, D., Khanna, R. (2023). History of Peritoneal Dialysis. In: Khanna, R., Krediet, R.T. (eds) Nolph and Gokal's Textbook of Peritoneal Dialysis. Springer, Cham. https://doi.org/10.1007/978-3-030-62087-5_1

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  • DOI: https://doi.org/10.1007/978-3-030-62087-5_1

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