Abstract
Objective: To analyze the traditional Chinese medicine (TCM) prescription regularity of Treatise on Febrile Diseases by using improved Apriori algorithm to obtain more efficient data mining. Methods: 113 formulae from Treatise on Febrile Diseases were collected and terms of herbs in this prescription were standardized. This paper put forward valid value index storage, and fast intersection operation to improve the efficiency of mining TCM data. The support-confidence-lift framework is adopted to evaluate the effectiveness of the rules and avoid the generation of meaningless rules. Results: 18 high-frequency herbs with occurrence of 10 times or above, including Licorice, Cassia Twig, Jujube and Ginseng, etc. Among18 high-frequency herbs, 52 combinations are obtained classical traditional herb pairs, such as Licorice-Cassia Twig, Jujube-Ginger and Ginger-Licorice, etc. Conclusion: The improved Apriori algorithm can be applied in the analysis on prescription compatibility and find out high-frequency herbs and herbs combinations with low storage consumption and high efficiency. The experimental result can provide references for clinical use of herbs which reveal the compatibility rule of the classical prescription.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Chen, G., Wang, Y., Qiu, J.: A research on the compatibility principles of formulas for spleen and stomach health from thousand golden prescriptions based on clustering mining and association rule mining technology. 8th International Symposium on Computational Intelligence and Design. IEEE (2015)
Jin, R., Zhi-jian, L., Chun-miao, X., et al: An improved association-mining research for exploring Chinese herbal property theory: based on data of the Shennong’s Classic of Materia Medica. J. Integr. Med. 11, 352–365 (2018)
Li, Y., et al: Herb network analysis for a famous TCM doctor’s prescriptions on treatment of rheumatoid arthritis. Evid.-Based Complement. Altern. Med. (2015)
Yang, M., et al: Navigating traditional Chinese medicine network pharmacology and computational tools. Evid.-Based Complement. Altern. Med. (2013)
Han, J., Pei, J., Yin, Y.: Mining frequent patterns without candidate generation. ACM sigmod record 1–12 (2000)
Huang, Y., Lin, Q., Li, Y.: Apriori-BM algorithm for mining association rules based on bit set matrix, 2nd. IEEE. IMCEC, 2580–2584 (2018)
Zhao, G.-b., Liu, Y.: An efficient bittable based frequent itemsets mining algorithm. J. Shandong Univ. 23–29 (2015)
Liu, Y., et al: Application and improvement discussion about Apriori algorithm of association rules mining in cases mining of influenza treated by contemporary famous old Chinese medicine. IEEE International Conference on Bioinformatics and Biomedicine Workshops 316–322 (2012)
Wang, Q., Jin, W., Song, X.: Research on the rules of apoplexy treatment based on optimized Apriori algorithm. J. Medical Inform. 62–67 (2017)
Wang, Q., Jin, W., Song, X.: Analysis on formula principles for “head wind” disease based on Apriori and clustering algorithm. J. Medical Inform. 56–64 (2019)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Switzerland AG
About this paper
Cite this paper
Li, M., Ren, X. (2021). TCM Prescription Compatibility Based on Improved Association Rules Algorithm. In: Sugumaran, V., Xu, Z., Zhou, H. (eds) Application of Intelligent Systems in Multi-modal Information Analytics. MMIA 2020. Advances in Intelligent Systems and Computing, vol 1233. Springer, Cham. https://doi.org/10.1007/978-3-030-51431-0_93
Download citation
DOI: https://doi.org/10.1007/978-3-030-51431-0_93
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-51430-3
Online ISBN: 978-3-030-51431-0
eBook Packages: Intelligent Technologies and RoboticsIntelligent Technologies and Robotics (R0)