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Endogenous Endophthalmitis

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Albert and Jakobiec's Principles and Practice of Ophthalmology

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Abstract

Endophthalmitis is a severe eye infection that can have severe vision-threatening complications. Endophthalmitis is usually caused by an exogenous source but may also be classified as endogenous as a result of hematogenous spread of a systemic infection. Endogenous endophthalmitis is often a diagnostic challenge and requires a high index of suspicion and a multidisciplinary approach. The causative microorganism may be bacterial or fungal, and appropriate and timely diagnosis and management frequently requires hospitalization. Both systemic and intravitreal antimicrobials are often necessary, and pars plana vitrectomy may be employed depending on the severity of the disease. Outcomes are generally poor but vary based on the disease duration, severity, and virulence of the offending pathogen. There are no established guidelines for the ideal management of these cases. This chapter will review common practices in the diagnosis and management of endogenous endophthalmitis.

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Authors and Affiliations

  1. Emory University Hospital, Atlanta, GA, USA

    Duncan Berry & Steven Yeh

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  1. Duncan Berry
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Correspondence to Steven Yeh .

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Editors and Affiliations

  1. Casey Eye Institute, Oregon Health & Science, Portland, OR, USA

    Daniel M. Albert

  2. Department of Ophthalmology, Massachusetts Eye and Ear, Massachusetts General Hospital, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Joan W. Miller

  3. Department of Ophthalmology, University of Illinois College of Medicine, University of Illinois at Chicago, Chicago, IL, USA

    Dimitri T. Azar

  4. Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA

    Lucy H. Young

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  1. Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA

    Lucia Sobrin

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Berry, D., Yeh, S. (2022). Endogenous Endophthalmitis. In: Albert, D.M., Miller, J.W., Azar, D.T., Young, L.H. (eds) Albert and Jakobiec's Principles and Practice of Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-030-42634-7_12

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