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Barriers Towards New Medicine: Personalized and Integrative Medicine Concepts

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Personalized Medicine in Healthcare Systems

Part of the book series: Europeanization and Globalization ((EAG,volume 5))

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Abstract

Technological advancements and enormous achievements in the biomedical field are presented daily. Still, everyday clinical environment lacks major breakthroughs often because of individual set-up of patients making them unique when it comes to management and treatment. A truly individual approach might therefore, transform quality of health-care and effectiveness of medicine. Implementation of such individualized medicine requires new global technologies and methods as well as a holistic view to a patient. In this paper, we discuss and present the personalized and integrative medicine paradigms as major drivers of radical changes in the system of health care that may solve some major issues that medicine faces today, i.e. globalization, new and fast growing infectious diseases, changes in behavior patterns of disease and aging population. Policy makers, health-authorities and public bodies are encouraged to enter this cross-sectorial debate and facilitate the public dialogue on such medical concept value and conditions for its success.

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Notes

  1. 1.

    Pavelić et al. (2016).

  2. 2.

    Bošnjak et al. (2008).

  3. 3.

    Kraljević et al. (2004).

  4. 4.

    Pavelić et al. (2015).

  5. 5.

    ESF (2012).

  6. 6.

    Taw (2015).

  7. 7.

    Snyderman and Weil (2002).

  8. 8.

    McLachlan (2010).

  9. 9.

    Rees and Weil (2001).

  10. 10.

    Catchpoole et al. (2010).

  11. 11.

    The Case for Personalized medicine (2014).

  12. 12.

    Badanes et al. (2012).

  13. 13.

    Fisher (2011).

  14. 14.

    Bell et al. (2012).

  15. 15.

    Tabish (2008).

  16. 16.

    Mathie (2003).

  17. 17.

    Pan et al. (2000).

  18. 18.

    Fontanarosa and Lundberg (1998).

  19. 19.

    Kermen et al. (2010).

  20. 20.

    Spear et al. (2001).

  21. 21.

    Ezzo et al. (2005).

  22. 22.

    Randall et al. (2001).

  23. 23.

    Munkholm et al. (1999).

  24. 24.

    Davinelli et al. (2015).

  25. 25.

    Cassidy (2011).

  26. 26.

    Laycock (1936).

  27. 27.

    Goodheart et al. (2006).

  28. 28.

    Dubord (2011).

  29. 29.

    Timmermans and Mauck (2005).

  30. 30.

    Ledford (2015).

  31. 31.

    Reynolds et al. (2014).

  32. 32.

    Aspinall and Hamermesh (2007).

  33. 33.

    Carr et al. (2012).

  34. 34.

    ESF (2007).

  35. 35.

    Ring et al. (2014).

  36. 36.

    Horrigan et al. (2012).

  37. 37.

    Eisenberg et al. (1993).

  38. 38.

    This paper is supported by the Croatian Science Foundation project “5709 - Perspectives of maintaining the social state: towards the transformation of social security systems for individuals in personalized medicine” and University of Rijeka research grants 13.11.1.1.11 and 13.11.1.2.01. We acknowledge the project “Research Infrastructure for Campus-based Laboratories at University of Rijeka”, financed by European Regional Development Fund (ERDF).

References

  • Aspinall MG, Hamermesh RG (2007) Realizing the promise of personalised medicine. Harvard Business Review. www.hbrreprints.org. October, pp 1–9

  • Badanes LS, Dmitrieva J, Watamura SE (2012) Understanding cortisol reactivity across the day at child care: the potential buffering role of secure attachments to caregivers. Early Child Res Q 27(1):156–165

    Article  Google Scholar 

  • Bell IR, Caspi O, Schwartz GE et al (2012) Integrative medicine and systemic outcomes research: issues in the emergence of a new model for primary health care. Arch Intern Med 162(2):133–140

    Article  Google Scholar 

  • Bošnjak H, Pavelić K, Kraljević Pavelić S (2008) Towards preventive medicine. High-throughput methods from molecular biology are about to change daily clinical practice. EMBO Rep 9:1056–1060

    Article  Google Scholar 

  • Carr DF, Alfirevic A, Pirmohamed M (2012) Pharmacogenomics: current state-of-the-art. Genes 5:430–443

    Article  Google Scholar 

  • Cassidy J (2011) Lobby Watch: The College of Medicine. BMJ 342:d3712

    Article  Google Scholar 

  • Catchpoole DR, Kennedy P, Scillicorn DR et al (2010) The curse of dimensionality: a blessing to personalized medicine. J Clin Oncol 28:e723–e724

    Article  Google Scholar 

  • Davinelli S, Bertoglio JC, Zarrelli A et al (2015) A randomized clinical trial evaluating the efficacy of an Anthocyanin-Maqui Berry Extract (Delphinol®) on oxidative stress biomarkers. J Am Coll Nutr 34(Suppl 1):28–33

    Article  Google Scholar 

  • Dubord G (2011) Part 12: systematic desensitization. Can Fam Physician 57(11):1299–1299

    Google Scholar 

  • Eisenberg DM, Kessler RC, Foster C et al (1993) Unconventional medicine in the United States. Prevalence, costs, and patterns of use. N Engl J Med 328:246–252

    Article  Google Scholar 

  • European Science Foundation (2007) EMRC White Paper. Present status and future strategy for medical research in Europe. The positive outcome of medical research 13–14

    Google Scholar 

  • European Science Foundation (2012) Forward Look: personalised medicine for the European citizen. Towards more precise medicine for the diagnosis, treatment and prevention of disease (iPM)European Science Foundation, Strasbourg

    Google Scholar 

  • Ezzo J, Vickers EA, Richardson MA et al (2005) Acupuncture-point stimulation for chemotherapy-induced nausea and vomiting. Jeanette J Clin Oncol 23(28):7188–7198

    Article  Google Scholar 

  • Fisher J (2011) The four domains model: connecting spirituality, health and well-being. Religions 2:17–28

    Article  Google Scholar 

  • Fontanarosa FB, Lundberg GD (1998) Alternative medicine meets science. JAMA 280(18):1618–1619

    Article  Google Scholar 

  • Goodheart CD, Kazdin AE, Sternberg RJ (2006) Evidence-based psychotherapy: where practice and research meet. American Psychological Association, Washington, DC, p 296

    Book  Google Scholar 

  • Horrigan B, Lewis S, Abrams D, Pechura C (2012) Integrative medicine in America—how integrative medicine is being practiced in clinical centers across the United States. Glob Adv Health Med 1(3):18–94

    Article  Google Scholar 

  • Kermen R, Hickner J, Brody H, Hasham I (2010) Family physicians believe the placebo effect is therapeutic but often use real drugs as placebos. Fam Med 42(9):636–642

    Google Scholar 

  • Kraljević S, Stambrook PJ, Pavelić K (2004) Accelerating drug discovery. EMBO Rep 5:837–842

    Article  Google Scholar 

  • Laycock SR (1936) The relation between physiology and medicine. Can Med Assoc J 35:434–438

    Google Scholar 

  • Ledford H (2015) Printed body parts come alive. Nature 520:273–273

    Article  Google Scholar 

  • Mathie RT (2003) The research evidence base for homeopathy: a fresh assessment of the literature. Homeopathy 92(2):84–91

    Article  Google Scholar 

  • McLachlan JC (2010) Integrative medicine and the point of credulity. Br Med J (Feature) 341:c6979

    Article  Google Scholar 

  • Munkholm H, Hansen HH, Rasmussen K (1999) Coenzyme Q10 treatment in serious heart failure. Biofactors 9:285–289

    Article  Google Scholar 

  • Pan CX, Morrison RS, Ness J et al (2000) Complementary and alternative medicine in the management of pain, dyspnea, and nausea and vomiting near the end of life: a systematic review. J Pain Sympt Manag 20:374–387

    Article  Google Scholar 

  • Pavelić K, Martinović T, Kraljević Pavelić S (2015) Do we understand the personalized medicine paradigm? EMBO Rep 16:133–136

    Article  Google Scholar 

  • Pavelić K, Sedić M, Kraljević Pavelić S (2016) Personalised medicine - the path to new medicine. In: Bodiroga-Vukobrat N, Rukavina D, Pavelic K, Sander GG (eds) Personalized medicine: a new medical and social challenge (Europeanization and globalization). Springer International Publishing, New York, pp 300–320

    Google Scholar 

  • Randall EM, Cynthia A et al (2001) A review of recent clinical trials of the nutritional supplement chlorella pyrenoidosa in the treatment of fibromyalgia, hypertension, and ulcerative colitis. Altern Ther Health Med 7(3):79–90

    Google Scholar 

  • Rees L, Weil A (2001) Integrated medicine: imbues orthodox medicine with the values of complementary medicine. Br Med J 322:119–120

    Article  Google Scholar 

  • Reynolds K, Sarangi S, Bardia A, Dizon DS (2014) Precision medicine and personalized breast cancer: combination pertuzumab therapy. Pharmacogenomics Pers Med 7(1):95–105

    Google Scholar 

  • Ring M, Brodsky M, Low Dog T, Sierpina V, Bailey M, Locke A, Kogan M, Rindfleisch JA, Saper R (2014) Supplemental digital content for: developing and implementing core competencies for integrative medicine fellowships. Acad Med 89(3):1–15

    Article  Google Scholar 

  • Snyderman R, Weil AT (2002) Integrative medicine: bringing medicine back to its roots. Arch Intern Med 162(4):395–397

    Article  Google Scholar 

  • Spear BB, Heath-Chiozzi M, Huff J (2001) Clinical application of pharmacogenetics. Trends Mol Med 7:201–204

    Article  Google Scholar 

  • Tabish SA (2008) Complementary and alternative healthcare: is it evidence-based? Int J Health Sci (Qassim) 2(1):5–9

    Google Scholar 

  • Taw MB (2015) Integrative medicine, or not integrative medicine: that is the question. J Integr Med 13(6):350–352

    Article  Google Scholar 

  • The Case for Personalized medicine (2014) Personalized medicine coalition, 4th edn. Washington, DC

    Google Scholar 

  • Timmermans S, Mauck A (2005) The promises and pitfalls of evidence-based medicine. Health Aff 24(1):18–28

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Juraj Dobrila University of Pula, Faculty of Medicine, Pula, Croatia

    Krešimir Pavelić

  2. Department of Biotechnology, Centre for High-Throughput Technologies, University of Rijeka, Rijeka, Croatia

    Krešimir Pavelić & Sandra Kraljević Pavelić

  3. Medical Centre CIIM Plus, Maribor, Slovenia

    Željko Perdija

Authors
  1. Krešimir Pavelić
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  2. Željko Perdija
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  3. Sandra Kraljević Pavelić
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Corresponding author

Correspondence to Krešimir Pavelić .

Editor information

Editors and Affiliations

  1. Faculty of Law, University of Rijeka, Rijeka, Croatia

    Nada Bodiroga-Vukobrat

  2. Croatian Academy of Sciences and Arts, Rijeka, Croatia

    Daniel Rukavina

  3. Juraj Dobrila University of Pula, Faculty of Medicine, Pula, Croatia

    Krešimir Pavelić

  4. Department of Biotechnology, Centre for High-Throughput Technologies, University of Rijeka, Rijeka, Croatia

    Krešimir Pavelić

  5. University of Applied Sciences, Ludwigsburg, Germany

    Gerald G. Sander

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Pavelić, K., Perdija, Ž., Kraljević Pavelić, S. (2019). Barriers Towards New Medicine: Personalized and Integrative Medicine Concepts. In: Bodiroga-Vukobrat, N., Rukavina, D., Pavelić, K., Sander, G.G. (eds) Personalized Medicine in Healthcare Systems. Europeanization and Globalization, vol 5. Springer, Cham. https://doi.org/10.1007/978-3-030-16465-2_19

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  • DOI: https://doi.org/10.1007/978-3-030-16465-2_19

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