Abstract
The increasing use of nanomaterials in biological applications raises numerous concerns about the dangers they might pose to living organisms. The rise in oxidative stress is usually the most readily observed effect induced by nanoparticles, with the measurement of lipid peroxidation levels being one of the most frequently used biological markers for its evaluation. Here, we describe the spectrophotometric and fluorimetric methods for determining the modifications of the malondialdehyde (MDA) level induced by many types of nanoparticles in in vitro and in vivo biological systems.
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Acknowledgement
This study was financially supported by the National Research Council of Higher Education, Romania, grant number 127TE/2010.
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Dinischiotu, A., Stanca, L., Gradinaru, D., Petrache, S.N., Radu, M., Serban, A.I. (2013). Lipid Peroxidation Due to In Vitro and In Vivo Exposure of Biological Samples to Nanoparticles. In: Armstrong, D., Bharali, D. (eds) Oxidative Stress and Nanotechnology. Methods in Molecular Biology, vol 1028. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-475-3_10
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DOI: https://doi.org/10.1007/978-1-62703-475-3_10
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