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In Vitro Assembly of Virus-Derived Designer Shells Around Inorganic Nanoparticles

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Virus-Derived Nanoparticles for Advanced Technologies

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1776))

Abstract

Nanoparticle-templated assembly of virus shells provides a promising approach to the production of hybrid nanomaterials and a potential avenue toward new mechanistic insights in virus phenomena originating in many-body effects, which cannot be understood from examining the properties of molecular subunits alone. This approach complements the successful molecular biology perspective traditionally used in virology, and promises a deeper understanding of viruses and virus-like particles through an expanded methodological toolbox. Here we present protocols for forming a virus coat protein shell around functionalized inorganic nanoparticles.

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Authors and Affiliations

  1. Chemistry Department, Indiana University, Bloomington, IN, USA

    Stella E. Vieweger, Irina B. Tsvetkova & Bogdan G. Dragnea

Authors
  1. Stella E. Vieweger
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  2. Irina B. Tsvetkova
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  3. Bogdan G. Dragnea
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Corresponding author

Correspondence to Bogdan G. Dragnea .

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Editors and Affiliations

  1. Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Stuttgart, Germany

    Christina Wege

  2. Department of Biological Chemistry, John Innes Centre, Norwich, United Kingdom

    George P. Lomonossoff

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Vieweger, S.E., Tsvetkova, I.B., Dragnea, B.G. (2018). In Vitro Assembly of Virus-Derived Designer Shells Around Inorganic Nanoparticles. In: Wege, C., Lomonossoff, G. (eds) Virus-Derived Nanoparticles for Advanced Technologies. Methods in Molecular Biology, vol 1776. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7808-3_19

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  • DOI: https://doi.org/10.1007/978-1-4939-7808-3_19

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7806-9

  • Online ISBN: 978-1-4939-7808-3

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