Abstract
Not only is human T cell development characterized by unique changes in surface marker expression, but it also requires specific growth factors and conditions to mimic and study T cell development in vitro. In this chapter, we provide an overview of the specific aspects that need attention when performing T cell differentiation cultures with human hematopoietic and T cell progenitors.
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© 2023 This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply
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Lambrechts, N., Liang, K.L., Velghe, I., Strubbe, S., Dolens, AC., Taghon, T. (2023). In Vitro Model Systems to Study Human T Cell Development. In: Bosselut, R., Vacchio, M.S. (eds) T-Cell Development. Methods in Molecular Biology, vol 2580. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2740-2_21
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DOI: https://doi.org/10.1007/978-1-0716-2740-2_21
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Publisher Name: Humana, New York, NY
Print ISBN: 978-1-0716-2739-6
Online ISBN: 978-1-0716-2740-2
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