Abstract
Mass deconvolution, the determination of proteoform precursor and fragment masses, is crucial for top-down proteomics data analysis. Here we describe the detailed procedure to run FLASHDeconv, an ultrafast, high-quality mass deconvolution tool. Both spectrum- and feature-level deconvolution results are obtainable in various output formats by FLASHDeconv. FLASHDeconv is runnable in different environments such as the command line and OpenMS workflows.
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Jeong, K., Kim, J., Kohlbacher, O. (2022). Mass Deconvolution of Top-Down Mass Spectrometry Datasets by FLASHDeconv. In: Sun, L., Liu, X. (eds) Proteoform Identification. Methods in Molecular Biology, vol 2500. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2325-1_11
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DOI: https://doi.org/10.1007/978-1-0716-2325-1_11
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