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Expanding the Biocatalysis Toolbox

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Green Chemistry in Drug Discovery

Part of the book series: Methods in Pharmacology and Toxicology ((MIPT))

Abstract

Research directed toward the development of biocatalytic platforms has been sparked by successful applications of enzymes for sustainable manufacturing of pharmaceutical compounds. This review describes recent progress in the development of ene-reductases, oxygenases, and enzymes for amide and amine synthesis, with a focus on academic and industrial collaborations.

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  1. Pfizer Worldwide Research and Development, Chemical Research and Development, Groton, CT, USA

    Rajesh Kumar, Carlos A. Martinez & John W. Wong

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  1. Rajesh Kumar
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  2. Carlos A. Martinez
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  1. World Wide Medicinal Chemistry, Pfizer Inc., San Diego, CA, USA

    Paul F. Richardson

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Kumar, R., Martinez, C.A., Wong, J.W. (2022). Expanding the Biocatalysis Toolbox. In: Richardson, P.F. (eds) Green Chemistry in Drug Discovery. Methods in Pharmacology and Toxicology. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1579-9_12

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  • DOI: https://doi.org/10.1007/978-1-0716-1579-9_12

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