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Biological Network Mining

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Modeling Transcriptional Regulation

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2328))

Abstract

In this book chapter, we introduce a pipeline to mine significant biomedical entities (or bioentities) in biological networks. Our focus is on prioritizing both bioentities themselves and the associations between bioentities in order to reveal their biological functions. We will introduce three tools BEERE, WIPER, and PAGER 2.0 that can be used together for network analysis and function interpretation: (1) BEERE is a network analysis tool for “Biomedical Entity Expansion, Ranking and Explorations,” (2) WIPER is an entity-to-entity association ranking tool, and (3) PAGER 2.0 is a service for gene enrichment analysis.

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Author information

Authors and Affiliations

  1. The University of Alabama at Birmingham, Birmingham, AL, USA

    Zongliang Yue, Da Yan, Guimu Guo & Jake Y. Chen

Authors
  1. Zongliang Yue
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  2. Da Yan
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  3. Guimu Guo
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  4. Jake Y. Chen
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Corresponding author

Correspondence to Da Yan .

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Editors and Affiliations

  1. Department of Biology, University of Alabama, Birmingham, AL, USA

    SHAHID MUKHTAR

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Yue, Z., Yan, D., Guo, G., Chen, J.Y. (2021). Biological Network Mining. In: MUKHTAR, S. (eds) Modeling Transcriptional Regulation. Methods in Molecular Biology, vol 2328. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1534-8_8

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  • DOI: https://doi.org/10.1007/978-1-0716-1534-8_8

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1533-1

  • Online ISBN: 978-1-0716-1534-8

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