Abstract
Nowadays, it is well established that many proteins or regions under physiological conditions lack a fixed three-dimensional structure and are intrinsically disordered. MobiDB is the main repository of protein disorder and mobility annotations, combining different data sources to provide an exhaustive overview of intrinsic disorder. MobiDB includes curated annotations from other databases, indirect disorder evidence from structural data, and disorder predictions from protein sequences. It provides an easy-to-use web server to visualize and explore disorder information. This chapter describes the data available in MobiDB, emphasizing how to use and access the intrinsic disorder data. MobiDB is available at URL http://mobidb.bio.unipd.it.
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Authors would like to thank Diana Battistella for helping us with manuscript proofreading.
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Monzon, A.M., Hatos, A., Necci, M., Piovesan, D., Tosatto, S.C.E. (2020). Exploring Protein Intrinsic Disorder with MobiDB. In: Kragelund, B.B., Skriver, K. (eds) Intrinsically Disordered Proteins. Methods in Molecular Biology, vol 2141. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0524-0_6
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DOI: https://doi.org/10.1007/978-1-0716-0524-0_6
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