Abstract
Numerous traits of interest in cardiovascular behavioral medicine reflect a complex interplay of genetic and environmental factors. In this chapter, we describe genetics and epigenetics, illustrated with examples of discoveries relevant to cardiovascular disease and its behavioral risk factors. We further discuss how genetic background interacts with environmental exposures and highlight examples of replicated gene x environment interaction. Finally, we discuss the principles of precision medicine and discuss the potential for leveraging genetic or epigenetic background to improve behavioral treatments.
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McCaffery, J.M. (2022). Genetics in Cardiovascular Behavioral Medicine. In: Waldstein, S.R., Kop, W.J., Suarez, E.C., Lovallo, W.R., Katzel, L.I. (eds) Handbook of Cardiovascular Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-85960-6_31
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